IL-1β knockdown inhibits cigarette smoke extract-induced inflammation and apoptosis in vascular smooth muscle cells

Hongfeng Jiang; Zhangqiang Guo; Kun Zeng; Haiyan Tang; Hanxuan Tan; Rui Min; Caihua Huang

doi:10.1371/journal.pone.0277719

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Open Access

Peer-reviewed

Research Article

IL-1β knockdown inhibits cigarette smoke extract-induced inflammation and apoptosis in vascular smooth muscle cells

Hongfeng Jiang ,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Validation, Writing – original draft

* E-mail: jhf2@sina.com

Affiliation Department of Geriatrics, Wuhan Fourth Hospital, Affiliated Puai Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China

https://orcid.org/0000-0002-9261-0433

⨯
Zhangqiang Guo,

Roles Conceptualization, Methodology

Affiliation Department of Emergency Medicine, Wuhan Fourth Hospital, Affiliated Puai Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯
Kun Zeng,

Roles Data curation, Supervision

Affiliation Department of Geriatrics, Wuhan Fourth Hospital, Affiliated Puai Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯
Haiyan Tang,

Roles Data curation

Affiliation Department of Geriatrics, Wuhan Fourth Hospital, Affiliated Puai Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯
Hanxuan Tan,

Roles Data curation

Affiliation Department of Geriatrics, Wuhan Fourth Hospital, Affiliated Puai Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯
Rui Min,

Roles Validation

Affiliation Department of Geriatrics, Wuhan Fourth Hospital, Affiliated Puai Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯
Caihua Huang

Roles Data curation

Affiliation Department of Geriatrics, Wuhan Fourth Hospital, Affiliated Puai Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China
⨯

IL-1β knockdown inhibits cigarette smoke extract-induced inflammation and apoptosis in vascular smooth muscle cells

Hongfeng Jiang,
Zhangqiang Guo,
Kun Zeng,
Haiyan Tang,
Hanxuan Tan,
Rui Min,
Caihua Huang

Published: February 15, 2023
https://doi.org/10.1371/journal.pone.0277719

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Apoptosis
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Smooth muscle cells
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Atherosclerosis
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Smoking habits
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Inflammation
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Cardiovascular diseases
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Gene expression
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Inflammatory diseases
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