Proteomic profiling of serum identifies a molecular signature that correlates with clinical outcomes in COPD

• Rania Dagher,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Bioscience COPD/IPF, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America

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• Paul Fogel,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Writing – original draft

  Affiliation Independent Consultant, Paris, France

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• Jingya Wang,

  Roles Data curation, Formal analysis, Investigation, Resources, Writing – original draft

  Affiliation Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America

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• David Soussan,

  Roles Data curation, Formal analysis, Resources

  Affiliations Inserm UMR1152, Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris Cité, Faculté de Médecine, Site Bichat, Paris, France, Laboratory of Excellence INFLAMEX, Université Paris-Cité, Paris, France

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• Chia-Chien Chiang,

  Roles Data curation, Formal analysis, Resources

  Affiliation Data Sciences and AI, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America

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• Jennifer Kearley,

  Roles Resources

  Affiliation Bioscience COPD/IPF, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America

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• Daniel Muthas,

  Roles Data curation

  Affiliation Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden

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• Camille Taillé,

  Roles Resources

  Affiliations Inserm UMR1152, Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris Cité, Faculté de Médecine, Site Bichat, Paris, France, Laboratory of Excellence INFLAMEX, Université Paris-Cité, Paris, France, Service de Pneumologie A - Groupement Hospitalier Universitaire Nord Bichat-Claude Bernard, Paris, France

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• Patrick Berger,

  Roles Resources

  Affiliation Inserm UMR1045, Université de Bordeaux, Service d’explorations Fonctionnelles Respiratoires, Centre Hospitalo-Universitaire de Bordeaux, Bordeaux, France

  https://orcid.org/0000-0003-4702-0343

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• Arnaud Bourdin,

  Roles Resources

  Affiliation Inserm UMR1046, Université de Montpellier, Département de Pneumologie et Addictologie, Centre Hospitalo-Universitaire de Montpellier, Montpellier, France

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• Cécile Chenivesse,

  Roles Resources

  Current address: Service de Pneumologie et Immuno-Allergologie, Centre Hospitalier Régional et Universitaire de Lille, Lille, France

  Affiliation Inserm UMR1158, Université Pierre et Marie Curie, Service de Pneumologie et Réanimation médicale, Centre Hospitalo-Universitaire La Pitié Salpêtrière, Paris, France

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• Sylvie Leroy,

  Roles Resources

  Affiliation Université de Nice and Service de Pneumologie Hôpital Pasteur, Centre Hospitalo-Universitaire de Nice, Nice, France

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• Gary Anderson,

  Roles Investigation, Resources

  Affiliation Lung Health Research Centre, Department of Pharmacology and Therapeutics, University of Melbourne, Melbourne, Victoria, Australia

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• Alison A. Humbles,

  Roles Resources

  Current address: Roche Innovation Centre Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland

  Affiliation Bioscience COPD/IPF, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America

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• Michel Aubier,

  Roles Investigation, Resources, Validation

  Affiliations Translational Science and Experimental Medicine, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America, Inserm UMR1152, Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris Cité, Faculté de Médecine, Site Bichat, Paris, France

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• Roland Kolbeck,

  Roles Conceptualization, Investigation, Project administration, Supervision, Validation, Writing – review & editing

  Current address: Spirovant Sciences, Philadelphia, Pennsylvania, United States of America

  Affiliation Bioscience COPD/IPF, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland, United States of America

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• Marina Pretolani ,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: marina.pretolani@inserm.fr

  Affiliations Inserm UMR1152, Physiopathologie et Epidémiologie des Maladies Respiratoires, Université Paris Cité, Faculté de Médecine, Site Bichat, Paris, France, Laboratory of Excellence INFLAMEX, Université Paris-Cité, Paris, France

  https://orcid.org/0000-0003-4576-5990

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•  [ ... ],
• on behalf of the COBRA Consortium

  ¶Membership of the COBRA Consortium is Provided in the Acknowledgments.

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