Upregulation of programmed death ligand-1 in tumor-associated macrophages affects chemotherapeutic response in ovarian cancer cells

Yong Soo Jang; Tae Wan Kim; Jae Sung Ryu; Hye Jeong Kong; Si Hyeong Jang; Gye Hyun Nam; Jae Hoon Kim; Seob Jeon

doi:10.1371/journal.pone.0277285

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Open Access

Peer-reviewed

Research Article

Upregulation of programmed death ligand-1 in tumor-associated macrophages affects chemotherapeutic response in ovarian cancer cells

Yong Soo Jang ,

Contributed equally to this work with: Yong Soo Jang, Tae Wan Kim

Roles Writing – original draft

Affiliation Department of Obstetrics and Gynecology, College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea

https://orcid.org/0000-0002-3470-7675

⨯
Tae Wan Kim ,

Contributed equally to this work with: Yong Soo Jang, Tae Wan Kim

Roles Data curation, Writing – original draft

Affiliations Soonchunhyang Innovative Convergence Research Center, Soonchunhyang University Cheonan Hospital, Cheonan, Korea, Department of Medical Life Science, Soonchunhyang University, Asan, Korea
⨯
Jae Sung Ryu,

Roles Project administration, Resources

Affiliations Soonchunhyang Innovative Convergence Research Center, Soonchunhyang University Cheonan Hospital, Cheonan, Korea, Department of Medical Life Science, Soonchunhyang University, Asan, Korea
⨯
Hye Jeong Kong,

Roles Methodology, Software

Affiliations Soonchunhyang Innovative Convergence Research Center, Soonchunhyang University Cheonan Hospital, Cheonan, Korea, Department of Medical Life Science, Soonchunhyang University, Asan, Korea
⨯
Si Hyeong Jang,

Roles Methodology, Visualization

Affiliation Department of Pathology, College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea
⨯
Gye Hyun Nam,

Roles Supervision

Affiliation Department of Obstetrics and Gynecology, College of Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea
⨯
Jae Hoon Kim,

Roles Supervision

Affiliation Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
⨯
Seob Jeon

Roles Conceptualization, Funding acquisition, Writing – review & editing

* E-mail: sjeon4595@gmail.com

Affiliation Department of Obstetrics and Gynecology, College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea

https://orcid.org/0000-0001-5230-1997

⨯

Upregulation of programmed death ligand-1 in tumor-associated macrophages affects chemotherapeutic response in ovarian cancer cells

Yong Soo Jang,
Tae Wan Kim,
Jae Sung Ryu,
Hye Jeong Kong,
Si Hyeong Jang,
Gye Hyun Nam,
Jae Hoon Kim,
Seob Jeon

Published: February 9, 2023
https://doi.org/10.1371/journal.pone.0277285

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Ovarian cancer
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Macrophages
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Cancer treatment
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Gastric cancer
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