Inhibition of c-Rel expression in myeloid and lymphoid cells with distearoyl -phosphatidylserine (DSPS) liposomal nanoparticles encapsulating therapeutic siRNA

Christian Bressy; Ali Zemani; Shreya Goyal; Davit Jishkariani; Chin Nien Lee; Youhai H. Chen

doi:10.1371/journal.pone.0276905

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Peer-reviewed

Research Article

Inhibition of c-Rel expression in myeloid and lymphoid cells with distearoyl -phosphatidylserine (DSPS) liposomal nanoparticles encapsulating therapeutic siRNA

Christian Bressy ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: chris.bressy@gmail.com (CB); yh.chen@siat.ac.cn (YHC)

Affiliation Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

https://orcid.org/0000-0001-6653-7546

⨯
Ali Zemani,

Roles Investigation, Methodology, Writing – review & editing

Affiliation Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Shreya Goyal,

Roles Methodology, Writing – review & editing

Affiliation Department of Biological Sciences, University of North Carolina, Charlotte, North Carolina, United States of America
⨯
Davit Jishkariani,

Roles Methodology, Resources

Affiliations Chemical and Nanoparticle Synthesis Core (CNSC), The University of Pennsylvania, Philadelphia, PA, United States of America, Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, United States of America

https://orcid.org/0000-0003-3771-2645

⨯
Chin Nien Lee,

Roles Writing – review & editing

Affiliation Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Youhai H. Chen

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: chris.bressy@gmail.com (CB); yh.chen@siat.ac.cn (YHC)

Affiliations Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Faculty of Pharmaceutical Sciences, CAS Shenzhen Institute of Advanced Technology, Shenzhen, China
⨯

Inhibition of c-Rel expression in myeloid and lymphoid cells with distearoyl -phosphatidylserine (DSPS) liposomal nanoparticles encapsulating therapeutic siRNA

Christian Bressy,
Ali Zemani,
Shreya Goyal,
Davit Jishkariani,
Chin Nien Lee,
Youhai H. Chen

Published: December 15, 2022
https://doi.org/10.1371/journal.pone.0276905

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