Inhibiting glutamine utilization creates a synthetic lethality for suppression of ATP citrate lyase in KRas-driven cancer cells

• Ahmet Hatipoglu,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Biological Sciences, Hunter College of the City University of New York, New York, New York, United States of America, Biochemistry Program, Graduate Center of the City University of New York, New York, New York, United States of America

  ⨯
• Deepak Menon,

  Roles Conceptualization, Data curation, Writing – review & editing

  Affiliations Department of Biological Sciences, Hunter College of the City University of New York, New York, New York, United States of America, Biochemistry Program, Graduate Center of the City University of New York, New York, New York, United States of America

  ⨯
• Talia Levy,

  Roles Data curation

  Affiliation Department of Biological Sciences, Hunter College of the City University of New York, New York, New York, United States of America

  ⨯
• Maria A. Frias,

  Roles Conceptualization, Writing – review & editing

  Affiliations Department of Biological Sciences, Hunter College of the City University of New York, New York, New York, United States of America, Department of Biology and Health Promotion, St Francis College, Brooklyn, New York, New York, United States of America

  ⨯
• David A. Foster

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: foster@genectr.hunter.cuny.edu

  Affiliations Department of Biological Sciences, Hunter College of the City University of New York, New York, New York, United States of America, Biochemistry Program, Graduate Center of the City University of New York, New York, New York, United States of America, Biology Program, Graduate Center of the City University of New York, New York, New York, United States of America, Department of Pharmacology, Weill Cornell Medicine, New York, New York, United States of America

  https://orcid.org/0000-0003-0900-6946

  ⨯