Targeting caveolae to pump bispecific antibody to TGF-β into diseased lungs enables ultra-low dose therapeutic efficacy

• Anil H. Kadam,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft

  Affiliation Proteogenomics Research Institute for Systems Medicine (PRISM), La Jolla, California, United States of America

  https://orcid.org/0000-0001-5897-8413

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• Kathirvel Kandasamy,

  Roles Investigation, Methodology, Writing – original draft

  Affiliation Proteogenomics Research Institute for Systems Medicine (PRISM), La Jolla, California, United States of America

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• Tim Buss,

  Roles Investigation, Methodology

  Affiliation Proteogenomics Research Institute for Systems Medicine (PRISM), La Jolla, California, United States of America

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• Brittany Cederstrom,

  Roles Investigation, Methodology

  Affiliation Proteogenomics Research Institute for Systems Medicine (PRISM), La Jolla, California, United States of America

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• Chun Yang,

  Roles Investigation, Methodology

  Affiliation Proteogenomics Research Institute for Systems Medicine (PRISM), La Jolla, California, United States of America

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• Sreekanth Narayanapillai,

  Roles Investigation

  Affiliation Proteogenomics Research Institute for Systems Medicine (PRISM), La Jolla, California, United States of America

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• Juan Rodriguez,

  Roles Investigation

  Affiliation Proteogenomics Research Institute for Systems Medicine (PRISM), La Jolla, California, United States of America

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• Michael D. Levin,

  Roles Methodology

  Affiliation Proteogenomics Research Institute for Systems Medicine (PRISM), La Jolla, California, United States of America

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• Jim Koziol,

  Roles Methodology, Validation

  Affiliation Proteogenomics Research Institute for Systems Medicine (PRISM), La Jolla, California, United States of America

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• Bogdan Olenyuk,

  Roles Methodology

  Affiliation Proteogenomics Research Institute for Systems Medicine (PRISM), La Jolla, California, United States of America

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• Zea Borok,

  Roles Funding acquisition, Writing – review & editing

  Affiliation Department of Medicine, UCSD School of Medicine, La Jolla, California, United States of America

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• Adrian Chrastina,

  Roles Methodology

  Affiliation Proteogenomics Research Institute for Systems Medicine (PRISM), La Jolla, California, United States of America

  https://orcid.org/0000-0002-4097-9773

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• Jan E. Schnitzer

  Roles Conceptualization, Funding acquisition, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: JSchnitzer@prism-sd.org

  Affiliations Proteogenomics Research Institute for Systems Medicine (PRISM), La Jolla, California, United States of America, Institute for Engineering in Medicine, UCSD, La Jolla, California, United States of America

  https://orcid.org/0000-0001-8211-9539

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