SPARE-Tau: A flortaucipir machine-learning derived early predictor of cognitive decline

• Jon B. Toledo ,

  Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  * E-mail: habes@uthscsa.edu (MH); jtoledo@houstonmethodist.org (JBT)

  Affiliations Department of Neurology, University of Florida College of Medicine, Gainesville, Florida, United States of America, Department of Neurology Houston Methodist Hospital, Houston, Texas, United States of America

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• Tanweer Rashid,

  Roles Formal analysis, Methodology, Software, Writing – review & editing

  Affiliation Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases, University of Texas Health Science Center San Antonio (UTHSCSA), San Antonio, Texas, United States of America

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• Hangfan Liu,

  Roles Methodology, Software, Writing – review & editing

  Affiliations Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases, University of Texas Health Science Center San Antonio (UTHSCSA), San Antonio, Texas, United States of America, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Lenore Launer,

  Roles Writing – review & editing

  Affiliation Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, Maryland, United States of America

  https://orcid.org/0000-0002-3238-7612

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• Leslie M. Shaw,

  Roles Writing – review & editing

  Affiliation Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Susan R. Heckbert,

  Roles Writing – review & editing

  Affiliation Department of Epidemiology and Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, United States of America

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• Michael Weiner,

  Roles Writing – review & editing

  Affiliations Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, California, United States of America, Department of Radiology, University of California, San Francisco, California, United States of America, Department of Medicine, University of California, San Francisco, California, United States of America, Department of Psychiatry, University of California, San Francisco, California, United States of America, Department of Neurology, University of California, San Francisco, California, United States of America

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• Sudha Seshadri,

  Roles Writing – review & editing

  Affiliation Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas, United States of America

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• Mohamad Habes ,

  Roles Conceptualization, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: habes@uthscsa.edu (MH); jtoledo@houstonmethodist.org (JBT)

  Affiliations Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases, University of Texas Health Science Center San Antonio (UTHSCSA), San Antonio, Texas, United States of America, Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Glenn Biggs Institute for Alzheimer’s and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas, United States of America

  https://orcid.org/0000-0001-9447-5805

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• for the Alzheimer’s Disease Neuroimaging Initiative

  ¶Membership of the Alzheimer’s Disease Neuroimaging Initiative Group is listed in the Acknowledgments.

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