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Open Access
Peer-reviewed
Research Article
Investigation of urinary metabolomics in a phase I hookworm vaccine trial in Gabon
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Madeleine Eunice Betouke Ongwe ,
Roles Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft
* E-mail: m.e.betouke_ongwe@lumc.nl
Affiliations Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands, Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon, Institut de Recherches en Écologie Tropicale, Centre National de la Recherche Scientifique et Technologique (CENAREST), Lambaréné, Gabon
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Yoanne D. Mouwenda,
Roles Investigation, Writing – review & editing
Affiliations Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands, Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon
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Koen A. Stam,
Roles Formal analysis, Writing – review & editing
Affiliation Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands
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Peter G. Kremsner,
Roles Writing – review & editing
Affiliation Institut für Tropenmedizin, Eberhad Karls Universität Tübingen, Tübingen, Germany
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Bertrand Lell,
Roles Writing – review & editing
Affiliations Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon, Division of Infectious Diseases and Tropical Medicine, Department of Medicine I, Medical University of Vienna, Vienna, Austria
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David Diemert,
Roles Writing – review & editing
Affiliation George Washington University, Washington, DC, United States of America
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Jeff Bethony,
Roles Writing – review & editing
Affiliation George Washington University, Washington, DC, United States of America
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Maria E. Bottazzi,
Roles Writing – review & editing
Affiliation Texas Children’s Hospital Center for Vaccine Development, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, United States of America
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Peter J. Hotez,
Roles Writing – review & editing
Affiliation Texas Children’s Hospital Center for Vaccine Development, National School of Tropical Medicine, Baylor College of Medicine, Houston, TX, United States of America
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Remko V. Leeuwen,
Roles Writing – review & editing
Affiliation Amsterdam Institute for Global Health and Development, Amsterdam, The Netherlands
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Martin P. Grobusch,
Roles Writing – review & editing
Affiliations Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon, Institut für Tropenmedizin, Eberhad Karls Universität Tübingen, Tübingen, Germany, Department of Infectious Diseases, Center of Tropical Medicine and Travel Medicine, Amsterdam University Medical Center, Amsterdam Public Health; Amsterdam Infection & Immunity, University of Amsterdam, Amsterdam, The Netherlands
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Ayola A. Adegnika,
Roles Funding acquisition, Writing – review & editing
Affiliations Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands, Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon, Institut für Tropenmedizin, Eberhad Karls Universität Tübingen, Tübingen, Germany, German Center for Infection Research (DZIF), Tübingen, Germany
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Oleg A. Mayboroda ,
Contributed equally to this work with: Oleg A. Mayboroda, Maria Yazdanbakhsh
Roles Formal analysis, Methodology, Supervision, Writing – review & editing
Affiliation Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands
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Maria Yazdanbakhsh
Contributed equally to this work with: Oleg A. Mayboroda, Maria Yazdanbakhsh
Roles Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing
Affiliation Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands
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Investigation of urinary metabolomics in a phase I hookworm vaccine trial in Gabon
- Madeleine Eunice Betouke Ongwe,
- Yoanne D. Mouwenda,
- Koen A. Stam,
- Peter G. Kremsner,
- Bertrand Lell,
- David Diemert,
- Jeff Bethony,
- Maria E. Bottazzi,
- Peter J. Hotez,
- Remko V. Leeuwen
- Published: September 26, 2022
- https://doi.org/10.1371/journal.pone.0275013