Analysis of the extent of limbic system changes in multiple sclerosis using FreeSurfer and voxel-based morphometry approaches

Amanda Frisosky Abuaf; Samuel R. Bunting; Sara Klein; Timothy Carroll; Jake Carpenter-Thompson; Adil Javed; Veronica Cipriani

doi:10.1371/journal.pone.0274778

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Open Access

Peer-reviewed

Research Article

Analysis of the extent of limbic system changes in multiple sclerosis using FreeSurfer and voxel-based morphometry approaches

Amanda Frisosky Abuaf,

Roles Conceptualization, Data curation, Formal analysis, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Neurology, The University of Wisconsin, Madison, WI, United States of America
⨯
Samuel R. Bunting,

Roles Formal analysis, Methodology, Resources, Supervision, Writing – review & editing

Affiliation Department of Psychiatry and Behavioral Neuroscience, The University of Chicago, Chicago, IL, United States of America

https://orcid.org/0000-0003-2186-5460

⨯
Sara Klein,

Roles Data curation, Writing – review & editing

Affiliation Department of Neurology, The University of Chicago, Chicago, IL, United States of America
⨯
Timothy Carroll,

Roles Resources, Visualization, Writing – review & editing

Affiliation Department of Radiology, The University of Chicago, Chicago, IL, United States of America
⨯
Jake Carpenter-Thompson,

Roles Resources, Software, Visualization, Writing – review & editing

Affiliation Department of Neurology, The University of Chicago, Chicago, IL, United States of America
⨯
Adil Javed ,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: ajaved@neurology.bsd.uchicago.edu

Affiliation Department of Neurology, The University of Chicago, Chicago, IL, United States of America

https://orcid.org/0000-0002-1834-7606

⨯
Veronica Cipriani

Roles Conceptualization, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Neurology, The University of Chicago, Chicago, IL, United States of America
⨯

Analysis of the extent of limbic system changes in multiple sclerosis using FreeSurfer and voxel-based morphometry approaches

Amanda Frisosky Abuaf,
Samuel R. Bunting,
Sara Klein,
Timothy Carroll,
Jake Carpenter-Thompson,
Adil Javed,
Veronica Cipriani

Published: September 22, 2022
https://doi.org/10.1371/journal.pone.0274778

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Multiple sclerosis
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Limbic system
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Atrophy
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Voxel-based morphometry
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Central nervous system
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Magnetic resonance imaging
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Nucleus accumbens
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Hippocampus
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