Expression of plant-produced anti-PD-L1 antibody with anoikis sensitizing activity in human lung cancer cells via., suppression on epithelial-mesenchymal transition

• Thareeya Phetphoung,

  Roles Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Graduate Program of Pharmaceutical Sciences and Technology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand, Center of Excellence in Plant-produced Pharmaceuticals, Chulalongkorn University, Bangkok, Thailand, Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand

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• Ashwini Malla,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Baiya Phytopharm Co., Ltd., Bangkok, Thailand

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• Kaewta Rattanapisit,

  Roles Methodology, Supervision, Writing – original draft

  Affiliation Baiya Phytopharm Co., Ltd., Bangkok, Thailand

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• Nuttapat Pisuttinusart,

  Roles Methodology, Writing – original draft

  Affiliations Graduate Program of Pharmaceutical Sciences and Technology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand, Center of Excellence in Plant-produced Pharmaceuticals, Chulalongkorn University, Bangkok, Thailand, Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand

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• Naruechai Damrongyot,

  Roles Methodology

  Affiliation Department of Biochemistry and Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand

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• Keerati Joyjamras,

  Roles Methodology

  Affiliation Pharmacology and Toxicology Unit, Department of Medical Science, Faculty of Science, Rangsit University, Pathum Thani, Thailand

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• Pithi Chanvorachote,

  Roles Methodology

  Affiliations Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand, Center of Excellence in Cancer Cell and Molecular Biology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand

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• Tanapati Phakham,

  Roles Methodology, Writing – original draft

  Affiliations Center of Excellence in Systems Biology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, Excellence Center for Cancer Immunotherapy, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand

  https://orcid.org/0000-0002-2167-7606

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• Tossapon Wongtangprasert,

  Roles Methodology

  Affiliations Center of Excellence in Systems Biology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, Excellence Center for Cancer Immunotherapy, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand, Excellence Chulalongkorn Comprehensive Cancer Center, King Chulalongkorn Memorial Hospital, Bangkok, Thailand

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• Richard Strasser,

  Roles Methodology, Writing – original draft

  Affiliation Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna, Austria

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• Chatchai Chaotham ,

  Roles Conceptualization, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Chatchai.C@chula.ac.th (CC); Waranyoo.P@chula.ac.th (WP)

  Affiliations Department of Biochemistry and Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand, Center of Excellence in Cancer Cell and Molecular Biology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand

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• Waranyoo Phoolcharoen

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Chatchai.C@chula.ac.th (CC); Waranyoo.P@chula.ac.th (WP)

  Affiliations Center of Excellence in Plant-produced Pharmaceuticals, Chulalongkorn University, Bangkok, Thailand, Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand

  https://orcid.org/0000-0001-5958-7406

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