Depletion of Scleraxis-lineage cells during tendon healing transiently impairs multi-scale restoration of tendon structure during early healing

Antonion Korcari; Samantha Muscat; Elizabeth McGinn; Mark R. Buckley; Alayna E. Loiselle

doi:10.1371/journal.pone.0274227

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Open Access

Peer-reviewed

Research Article

Depletion of Scleraxis-lineage cells during tendon healing transiently impairs multi-scale restoration of tendon structure during early healing

Antonion Korcari,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Visualization, Writing – original draft, Writing – review & editing

Affiliations Department of Orthopaedics & Rehabilitation, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, United States of America, Department of Biomedical Engineering, University of Rochester, Rochester, NY, United States of America

https://orcid.org/0000-0002-5964-5212

⨯
Samantha Muscat,

Roles Data curation

Affiliation Department of Orthopaedics & Rehabilitation, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, United States of America
⨯
Elizabeth McGinn,

Roles Formal analysis, Methodology

Affiliations Department of Orthopaedics & Rehabilitation, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, United States of America, Department of Biomedical Engineering, University of Rochester, Rochester, NY, United States of America
⨯
Mark R. Buckley,

Roles Formal analysis, Methodology, Resources, Validation, Writing – review & editing

Affiliations Department of Orthopaedics & Rehabilitation, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, United States of America, Department of Biomedical Engineering, University of Rochester, Rochester, NY, United States of America
⨯
Alayna E. Loiselle

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: Alayna_Loiselle@URMC.Rochester.edu

Affiliations Department of Orthopaedics & Rehabilitation, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, United States of America, Department of Biomedical Engineering, University of Rochester, Rochester, NY, United States of America
⨯

Depletion of Scleraxis-lineage cells during tendon healing transiently impairs multi-scale restoration of tendon structure during early healing

Antonion Korcari,
Samantha Muscat,
Elizabeth McGinn,
Mark R. Buckley,
Alayna E. Loiselle

Published: October 14, 2022
https://doi.org/10.1371/journal.pone.0274227

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