Functionally impaired isoforms regulate TMPRSS6 proteolytic activity

Sébastien P. Dion; Antoine Désilets; Gabriel Lemieux; Richard Leduc

doi:10.1371/journal.pone.0273825

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Open Access

Peer-reviewed

Research Article

Functionally impaired isoforms regulate TMPRSS6 proteolytic activity

Sébastien P. Dion,

Roles Conceptualization, Data curation, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

Affiliations Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada, Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada

https://orcid.org/0000-0002-8961-0782

⨯
Antoine Désilets,

Roles Conceptualization, Investigation, Methodology, Project administration, Writing – review & editing

Affiliations Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada, Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada
⨯
Gabriel Lemieux,

Roles Data curation, Writing – review & editing

Affiliations Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada, Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada

https://orcid.org/0000-0002-2313-5528

⨯
Richard Leduc

Roles Conceptualization, Funding acquisition, Writing – review & editing

* E-mail: Richard.Leduc@USherbrooke.ca

Affiliations Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada, Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec, Canada
⨯

Functionally impaired isoforms regulate TMPRSS6 proteolytic activity

Sébastien P. Dion,
Antoine Désilets,
Gabriel Lemieux,
Richard Leduc

Published: August 31, 2022
https://doi.org/10.1371/journal.pone.0273825

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Immunoprecipitation
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Transfection
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Homeostasis
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Serine proteases
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Co-immunoprecipitation
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Hepatocytes
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Interaction networks
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Molting
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