Corneal epithelium in keratoconus underexpresses active NRF2 and a subset of oxidative stress-related genes

• Tatiana Lupasco,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), Toulouse University, CNRS, Inserm, Paul Sabatier Toulouse III University, Toulouse, France

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• Zhiguo He,

  Roles Conceptualization, Data curation, Investigation, Methodology, Validation, Writing – original draft

  Affiliation Laboratory "Biology, Engineering, and Imaging of Corneal Graft", BiiGC, EA2521, Faculty of Medicine, Jean Monnet University, Saint-Etienne, France

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• Myriam Cassagne,

  Roles Investigation, Resources, Writing – original draft

  Affiliations Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), Toulouse University, CNRS, Inserm, Paul Sabatier Toulouse III University, Toulouse, France, Department of Ophthalmology, Toulouse University Hospital, Toulouse, France

  https://orcid.org/0000-0002-7554-661X

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• Tomy Sagnial,

  Roles Data curation, Investigation

  Affiliation Laboratory "Biology, Engineering, and Imaging of Corneal Graft", BiiGC, EA2521, Faculty of Medicine, Jean Monnet University, Saint-Etienne, France

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• Lise Brion,

  Roles Data curation, Investigation, Resources

  Affiliation Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), Toulouse University, CNRS, Inserm, Paul Sabatier Toulouse III University, Toulouse, France

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• Pierre Fournié,

  Roles Conceptualization, Project administration, Supervision, Writing – original draft

  Affiliations Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), Toulouse University, CNRS, Inserm, Paul Sabatier Toulouse III University, Toulouse, France, Department of Ophthalmology, Toulouse University Hospital, Toulouse, France

  https://orcid.org/0000-0002-9224-2351

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• Philippe Gain,

  Roles Supervision, Validation

  Affiliations Laboratory "Biology, Engineering, and Imaging of Corneal Graft", BiiGC, EA2521, Faculty of Medicine, Jean Monnet University, Saint-Etienne, France, Department of Ophthalmology, St Etienne University Hospital, Saint-Etienne, France

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• Gilles Thuret,

  Roles Supervision, Validation

  Affiliations Laboratory "Biology, Engineering, and Imaging of Corneal Graft", BiiGC, EA2521, Faculty of Medicine, Jean Monnet University, Saint-Etienne, France, Department of Ophthalmology, St Etienne University Hospital, Saint-Etienne, France

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• Michèle Allouche,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Supervision, Validation, Writing – original draft

  Affiliation Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), Toulouse University, CNRS, Inserm, Paul Sabatier Toulouse III University, Toulouse, France

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• François Malecaze,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft

  Affiliations Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), Toulouse University, CNRS, Inserm, Paul Sabatier Toulouse III University, Toulouse, France, Department of Ophthalmology, Toulouse University Hospital, Toulouse, France

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• Michel Simon ,

  Contributed equally to this work with: Michel Simon, Stéphane D. Galiacy

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft

  * E-mail: michel.simon@inserm.fr (MS); stephane.galiacy@inserm.fr (SDG)

  Affiliation Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), Toulouse University, CNRS, Inserm, Paul Sabatier Toulouse III University, Toulouse, France

  https://orcid.org/0000-0003-3655-6329

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• Stéphane D. Galiacy

  Contributed equally to this work with: Michel Simon, Stéphane D. Galiacy

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft

  * E-mail: michel.simon@inserm.fr (MS); stephane.galiacy@inserm.fr (SDG)

  Affiliations Toulouse Institute for Infectious and Inflammatory Diseases (Infinity), Toulouse University, CNRS, Inserm, Paul Sabatier Toulouse III University, Toulouse, France, Department of Ophthalmology, Toulouse University Hospital, Toulouse, France

  https://orcid.org/0000-0003-2273-8105

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