Biperiden for prevention of post-traumatic epilepsy: A protocol of a double-blinded placebo-controlled randomized clinical trial (BIPERIDEN trial)

• Maira Licia Foresti ,

  Contributed equally to this work with: Maira Licia Foresti, Eliana Garzon

  Roles Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Validation, Writing – original draft

  Affiliations Neurology Neuroscience Postgraduation Program, Physiology Department, Universidade Federal de São Paulo, São Paulo, Brasil, Sociedade Beneficente de Senhoras Hospital Sírio-Libanês, São Paulo, SP, Brazil, Instituto D’Or de Pesquisa e Ensino, São Paulo, SP, Brasil

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• Eliana Garzon ,

  Contributed equally to this work with: Maira Licia Foresti, Eliana Garzon

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliations Sociedade Beneficente de Senhoras Hospital Sírio-Libanês, São Paulo, SP, Brazil, Department of Neurology, Division of Neurologic Clinic, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo-SP, Brazil

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• Carla Cristina Gomes Pinheiro,

  Roles Data curation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

  Affiliation Sociedade Beneficente de Senhoras Hospital Sírio-Libanês, São Paulo, SP, Brazil

  https://orcid.org/0000-0002-7613-6997

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• Rafael Leite Pacheco,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliations Departamento de Medicina, Centro Universitário São Camilo, São Paulo, SP, Brazil, Center of Health Technology Assessment, Sociedade Beneficente de Senhoras Hospital Sírio-Libanês, São Paulo, SP, Brazil

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• Rachel Riera,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliations Center of Health Technology Assessment, Sociedade Beneficente de Senhoras Hospital Sírio-Libanês, São Paulo, SP, Brazil, Discipline of Evidence-based Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil

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• Luiz Eugênio Mello

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: lemello@unifesp.br

  Affiliations Neurology Neuroscience Postgraduation Program, Physiology Department, Universidade Federal de São Paulo, São Paulo, Brasil, Sociedade Beneficente de Senhoras Hospital Sírio-Libanês, São Paulo, SP, Brazil, Instituto D’Or de Pesquisa e Ensino, São Paulo, SP, Brasil

  https://orcid.org/0000-0002-6969-1108

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