ICSI in non-male factor infertility patients does not alter metabolomic signature in sibling embryos as evidenced by sensitivity enhanced nuclear magnetic resonance (NMR) spectroscopy

• Ameya Jijo ,

  Contributed equally to this work with: Ameya Jijo, Aswathi Cheredath

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Reproductive Science, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India

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• Aswathi Cheredath ,

  Contributed equally to this work with: Ameya Jijo, Aswathi Cheredath

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Reproductive Science, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India

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• Shubhashree Uppangala,

  Roles Formal analysis, Writing – original draft

  Affiliation Department of Reproductive Science, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India

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• Vani Lakshmi R.,

  Roles Formal analysis

  Affiliation Department of Data Science, Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, India

  ⨯
• David Joseph,

  Roles Formal analysis

  Affiliation NMR Research Centre, Indian Institute of Science, Bangalore, India

  ⨯
• Huidrom Yaiphaba Meitei,

  Roles Formal analysis

  Affiliation Department of Reproductive Science, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India

  ⨯
• Gitanjali Asampille,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Reproductive Science, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India

  ⨯
• Pratap Kumar,

  Roles Writing – review & editing

  Affiliation Department of Reproductive Medicine and Surgery, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India

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• Nagana Gowda G. A.,

  Roles Writing – original draft, Writing – review & editing

  Affiliation Northwest Metabolomics Research Center, Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, United States of America

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• Guruprasad Kalthur,

  Roles Writing – review & editing

  Affiliation Department of Reproductive Science, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India

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• Borut Kovacic,

  Roles Writing – review & editing

  Affiliation Department of Reproductive Medicine, University Medical Centre Maribor, Maribor, Slovenia

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• Satish Kumar Adiga

  Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: satish.adiga@manipal.edu

  Affiliation Department of Reproductive Science, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India

  https://orcid.org/0000-0002-2897-4697

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