Metabolic analyses reveal dysregulated NAD⁺ metabolism and altered mitochondrial state in ulcerative colitis

• Yu Hui Kang ,

  Contributed equally to this work with: Yu Hui Kang, Sarah A. Tucker

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Current address: Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore

  Affiliations Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, United States of America, Division of Gastroenterology, Hepatology and Nutrition, Boston Children’s Hospital, Boston, MA, United States of America

  https://orcid.org/0000-0001-9081-3969

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• Sarah A. Tucker ,

  Contributed equally to this work with: Yu Hui Kang, Sarah A. Tucker

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, United States of America

  https://orcid.org/0000-0001-8885-0154

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• Silvia F. Quevedo,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital, Boston, MA, United States of America, Department of Medicine, Harvard Medical School, Boston, MA, United States of America

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• Aslihan Inal,

  Roles Data curation, Formal analysis, Methodology

  Current address: Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany

  Affiliation Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, United States of America

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• Joshua R. Korzenik,

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Writing – review & editing

  Affiliations Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital, Boston, MA, United States of America, Department of Medicine, Harvard Medical School, Boston, MA, United States of America

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• Marcia C. Haigis

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Writing – review & editing

  * E-mail: Marcia_haigis@hms.harvard.edu

  Affiliation Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, United States of America

  https://orcid.org/0000-0003-2530-2681

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