Triple-negative breast cancer influences a mixed M1/M2 macrophage phenotype associated with tumor aggressiveness

Kristine Cate S. Pe; Rattana Saetung; Varalee Yodsurang; Chatchai Chaotham; Koramit Suppipat; Pithi Chanvorachote; Supannikar Tawinwung

doi:10.1371/journal.pone.0273044

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Open Access

Peer-reviewed

Research Article

Triple-negative breast cancer influences a mixed M1/M2 macrophage phenotype associated with tumor aggressiveness

Kristine Cate S. Pe,

Roles Data curation, Formal analysis, Investigation, Visualization, Writing – original draft

Affiliation Faculty of Pharmaceutical Sciences, Department of Pharmacology and Physiology, Chulalongkorn University, Bangkok, Thailand
⨯
Rattana Saetung,

Roles Formal analysis, Investigation

Affiliation Faculty of Pharmaceutical Sciences, Department of Pharmacology and Physiology, Chulalongkorn University, Bangkok, Thailand
⨯
Varalee Yodsurang,

Roles Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Faculty of Pharmaceutical Sciences, Department of Pharmacology and Physiology, Chulalongkorn University, Bangkok, Thailand
⨯
Chatchai Chaotham,

Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing

Affiliation Faculty of Pharmaceutical Sciences, Department of Biochemistry and Microbiology, Chulalongkorn University, Bangkok, Thailand
⨯
Koramit Suppipat,

Roles Conceptualization, Methodology, Resources, Supervision, Writing – review & editing

Affiliations Faculty of Medicine, Department of Research Affair, Chulalongkorn University, Bangkok, Thailand, Cellular Immunotherapy Research Unit, Chulalongkorn University, Bangkok, Thailand
⨯
Pithi Chanvorachote,

Roles Conceptualization, Funding acquisition, Supervision

Affiliation Faculty of Pharmaceutical Sciences, Department of Pharmacology and Physiology, Chulalongkorn University, Bangkok, Thailand
⨯
Supannikar Tawinwung

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

* E-mail: supannikar.T@pharm.chula.ac.th

Affiliations Faculty of Pharmaceutical Sciences, Department of Pharmacology and Physiology, Chulalongkorn University, Bangkok, Thailand, Cellular Immunotherapy Research Unit, Chulalongkorn University, Bangkok, Thailand

https://orcid.org/0000-0003-2151-4580

⨯

Triple-negative breast cancer influences a mixed M1/M2 macrophage phenotype associated with tumor aggressiveness

Kristine Cate S. Pe,
Rattana Saetung,
Varalee Yodsurang,
Chatchai Chaotham,
Koramit Suppipat,
Pithi Chanvorachote,
Supannikar Tawinwung

Published: August 12, 2022
https://doi.org/10.1371/journal.pone.0273044

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Breast cancer
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Macrophages
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Cytokines
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Gene expression
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Monocytes
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Cancer treatment
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Cell proliferation
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Differentiated tumors
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