Stenoparib, an inhibitor of cellular poly (ADP-ribose) polymerases (PARPs), blocks in vitro replication of SARS-CoV-2 variants

• Katherine E. Zarn ,

  Contributed equally to this work with: Katherine E. Zarn, Sierra A. Jaramillo

  Roles Data curation, Formal analysis, Investigation, Visualization, Writing – review & editing

  Affiliation Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, United States of America

  https://orcid.org/0000-0002-7953-0295

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• Sierra A. Jaramillo ,

  Contributed equally to this work with: Katherine E. Zarn, Sierra A. Jaramillo

  Roles Formal analysis, Investigation

  Affiliation Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, United States of America

  ⨯
• Anthony R. Zapata,

  Roles Investigation

  Affiliation Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, United States of America

  ⨯
• Nathan E. Stone,

  Roles Methodology, Writing – review & editing

  Affiliation Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, United States of America

  https://orcid.org/0000-0002-8723-359X

  ⨯
• Ashley N. Jones,

  Roles Investigation

  Affiliation Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, United States of America

  ⨯
• Haley E. Nunnally,

  Roles Investigation

  Affiliation Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, United States of America

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• Erik W. Settles,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliations Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, United States of America, Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona, United States of America

  ⨯
• Ken Ng,

  Roles Visualization

  Affiliation Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, United States of America

  ⨯
• Paul S. Keim,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, United States of America, Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona, United States of America

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• Steen Knudsen,

  Roles Conceptualization, Funding acquisition, Project administration

  Affiliation Allarity Therapeutics Europe, Hørsholm, Denmark

  https://orcid.org/0000-0001-9503-2504

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• Patricia M. Nuijten,

  Roles Investigation

  Affiliation Viroclinics-DDL, Rotterdam, The Netherlands

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• Aloys S. L. Tijsma,

  Roles Investigation, Project administration, Writing – review & editing

  Affiliation Viroclinics-DDL, Rotterdam, The Netherlands

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• Christopher T. French

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: ctfrench@nau.edu

  Affiliations Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, United States of America, Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona, United States of America, COVID-19 Testing Service Center, Pathogen and Microbiome Institute, Northern Arizona University, Flagstaff, Arizona, United States of America

  https://orcid.org/0000-0001-5157-7078

  ⨯