Network diffusion model predicts neurodegeneration in limb-onset Amyotrophic Lateral Sclerosis

• Anjan Bhattarai ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: anbhattarai@ucdavis.edu

  Current address: Department of Biomedical Engineering and Department of Neurology, University of California Davis, Davis, California, United States of America

  Affiliations Department of Psychiatry, Monash University, Clayton, Victoria, Australia, Monash Biomedical Imaging, Monash University, Clayton, Victoria, Australia

  https://orcid.org/0000-0002-9178-6509

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• Zhaolin Chen,

  Roles Methodology, Supervision, Validation, Writing – review & editing

  Affiliation Monash Biomedical Imaging, Monash University, Clayton, Victoria, Australia

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• Phyllis Chua,

  Roles Funding acquisition, Investigation, Resources, Supervision, Writing – review & editing

  Affiliations Department of Psychiatry, Monash University, Clayton, Victoria, Australia, Statewide Progressive Neurological Disease Service, Calvary Health Care Bethlehem, South Caulfield, Victoria, Australia

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• Paul Talman,

  Roles Funding acquisition, Investigation, Resources, Supervision, Writing – review & editing

  Affiliation School of Medicine, Faculty of Health, Deakin University, Geelong, Victoria, Australia

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• Susan Mathers,

  Roles Funding acquisition, Investigation, Resources, Writing – review & editing

  Affiliation Statewide Progressive Neurological Disease Service, Calvary Health Care Bethlehem, South Caulfield, Victoria, Australia

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• Caron Chapman,

  Roles Resources, Writing – review & editing

  Affiliation Neurosciences Department, University Hospital, Geelong, Victoria, Australia

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• James Howe,

  Roles Resources, Writing – review & editing

  Affiliation Statewide Progressive Neurological Disease Service, Calvary Health Care Bethlehem, South Caulfield, Victoria, Australia

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• C. M. Sarah Lee,

  Roles Resources, Writing – review & editing

  Affiliation Statewide Progressive Neurological Disease Service, Calvary Health Care Bethlehem, South Caulfield, Victoria, Australia

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• Yenni Lie,

  Roles Resources, Writing – review & editing

  Affiliation Statewide Progressive Neurological Disease Service, Calvary Health Care Bethlehem, South Caulfield, Victoria, Australia

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• Govinda R. Poudel ,

  Contributed equally to this work with: Govinda R. Poudel, Gary F. Egan

  Roles Conceptualization, Methodology, Resources, Software, Validation, Visualization, Writing – review & editing

  Affiliation Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia

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• Gary F. Egan

  Contributed equally to this work with: Govinda R. Poudel, Gary F. Egan

  Roles Conceptualization, Resources, Supervision, Writing – review & editing

  Affiliation Monash Biomedical Imaging, Monash University, Clayton, Victoria, Australia

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