An assessment of prevalence of Type 1 CFI rare variants in European AMD, and why lack of broader genetic data hinders development of new treatments and healthcare access

• Amy V. Jones,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Gyroscope Therapeutics Limited, London, United Kingdom

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• Darin Curtiss,

  Roles Writing – review & editing

  Affiliation Gyroscope Therapeutics Limited, London, United Kingdom

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• Claire Harris,

  Roles Writing – review & editing

  Affiliation Gyroscope Therapeutics Limited, London, United Kingdom

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• Tom Southerington,

  Roles Data curation

  Affiliations Finnish Biobank Cooperative–FINBB, Turku, Finland, University of Turku, Turku, Finland

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• Marco Hautalahti,

  Roles Data curation

  Affiliation Finnish Biobank Cooperative–FINBB, Turku, Finland

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• Pauli Wihuri,

  Roles Data curation

  Affiliation Finnish Biobank Cooperative–FINBB, Turku, Finland

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• Johanna Mäkelä,

  Roles Data curation

  Affiliation Finnish Biobank Cooperative–FINBB, Turku, Finland

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• Roosa E. Kallionpää,

  Roles Data curation

  Affiliation Auria Biobank, Turku University Hospital and University of Turku, Turku, Finland

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• Enni Makkonen,

  Roles Data curation

  Affiliation Finnish Clinical Biobank Tampere, Tampere, Finland

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• Theresa Knopp,

  Roles Data curation

  Affiliation Helsinki Biobank, HUS, Helsinki University Hospital, Helsinki, Finland

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• Arto Mannermaa,

  Roles Data curation

  Affiliation Biobank of Eastern Finland, KYS, Kuopio, Finland

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• Erna Mäkinen,

  Roles Data curation

  Affiliation Biobank of Central Finland, Hospital Nova of Central Finland, Jyväskylä, Finland

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• Anne-Mari Moilanen,

  Roles Data curation

  Affiliation Biobank Borealis of Northern Finland, Oulu University Hospital, Oulu, Finland

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• Tongalp H. Tezel,

  Roles Writing – review & editing

  Affiliation Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University College of Physicians and Surgeons, Columbia University Medical Center, New York, NY, United States of America

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• on behalf of the SCOPE Study group ,

  ¶Membership of the SCOPE Study group is provided in the Acknowledgments.

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•  [ ... ],
• Nadia K. Waheed

  Roles Conceptualization, Funding acquisition

  * E-mail: nadiakwaheed@gmail.com

  Affiliations Gyroscope Therapeutics Limited, London, United Kingdom, Department of Ophthalmology, Tufts University School of Medicine, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0002-8229-7519

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