Multi-omics assessment of dilated cardiomyopathy using non-negative matrix factorization

Rewati Tappu; Jan Haas; David H. Lehmann; Farbod Sedaghat-Hamedani; Elham Kayvanpour; Andreas Keller; Hugo A. Katus; Norbert Frey; Benjamin Meder

doi:10.1371/journal.pone.0272093

Loading metrics

Open Access

Peer-reviewed

Research Article

Multi-omics assessment of dilated cardiomyopathy using non-negative matrix factorization

Rewati Tappu,

Roles Conceptualization, Formal analysis, Writing – original draft

Affiliations Institute for Cardiomyopathies Heidelberg (ICH), Heart Center Heidelberg, University of Heidelberg, Heidelberg, Germany, DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Mannheim, Germany

https://orcid.org/0000-0003-0902-7114

⨯
Jan Haas,

Roles Data curation, Resources

Affiliations Institute for Cardiomyopathies Heidelberg (ICH), Heart Center Heidelberg, University of Heidelberg, Heidelberg, Germany, DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Mannheim, Germany
⨯
David H. Lehmann,

Roles Formal analysis

Affiliation Institute for Cardiomyopathies Heidelberg (ICH), Heart Center Heidelberg, University of Heidelberg, Heidelberg, Germany
⨯
Farbod Sedaghat-Hamedani,

Roles Data curation

Affiliations Institute for Cardiomyopathies Heidelberg (ICH), Heart Center Heidelberg, University of Heidelberg, Heidelberg, Germany, DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Mannheim, Germany
⨯
Elham Kayvanpour,

Roles Data curation

Affiliations Institute for Cardiomyopathies Heidelberg (ICH), Heart Center Heidelberg, University of Heidelberg, Heidelberg, Germany, DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Mannheim, Germany
⨯
Andreas Keller,

Roles Writing – review & editing

Affiliation Department of Clinical Bioinformatics, Medical Faculty, Saarland University, Saarbrücken, Germany
⨯
Hugo A. Katus,

Roles Funding acquisition, Resources, Writing – review & editing

Affiliations Institute for Cardiomyopathies Heidelberg (ICH), Heart Center Heidelberg, University of Heidelberg, Heidelberg, Germany, DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Mannheim, Germany
⨯
Norbert Frey,

Roles Resources

Affiliations Institute for Cardiomyopathies Heidelberg (ICH), Heart Center Heidelberg, University of Heidelberg, Heidelberg, Germany, DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Mannheim, Germany
⨯
Benjamin Meder

Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

* E-mail: Benjamin.Meder@med.uni-heidelberg.de

Affiliations Institute for Cardiomyopathies Heidelberg (ICH), Heart Center Heidelberg, University of Heidelberg, Heidelberg, Germany, DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, Mannheim, Germany, Department of Genetics, Stanford University School of Medicine, Palo Alto, California, United States of America

https://orcid.org/0000-0003-0741-2633

⨯

Multi-omics assessment of dilated cardiomyopathy using non-negative matrix factorization

Rewati Tappu,
Jan Haas,
David H. Lehmann,
Farbod Sedaghat-Hamedani,
Elham Kayvanpour,
Andreas Keller,
Hugo A. Katus,
Norbert Frey,
Benjamin Meder

Published: August 18, 2022
https://doi.org/10.1371/journal.pone.0272093

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

DNA methylation
Is the Subject Area "DNA methylation" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Gene ontologies
Is the Subject Area "Gene ontologies" applicable to this article?

Thanks for your feedback.
Treatment guidelines
Is the Subject Area "Treatment guidelines" applicable to this article?

Thanks for your feedback.
Genetic networks
Is the Subject Area "Genetic networks" applicable to this article?

Thanks for your feedback.
Extracellular matrix
Is the Subject Area "Extracellular matrix" applicable to this article?

Thanks for your feedback.
Factor analysis
Is the Subject Area "Factor analysis" applicable to this article?

Thanks for your feedback.
Hierarchical clustering
Is the Subject Area "Hierarchical clustering" applicable to this article?

Thanks for your feedback.