Timely administration of tocilizumab improves outcome of hospitalized COVID-19 patients

• Abraham Rutgers ,

  Contributed equally to this work with: Abraham Rutgers, Peter E. Westerweel

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: a.rutgers@umcg.nl

  Affiliation Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, The Netherlands

  ⨯
• Peter E. Westerweel ,

  Contributed equally to this work with: Abraham Rutgers, Peter E. Westerweel

  Roles Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands

  https://orcid.org/0000-0002-0746-7039

  ⨯
• Bronno van der Holt,

  Roles Conceptualization, Data curation, Formal analysis, Software, Writing – original draft, Writing – review & editing

  Affiliation HOVON Data Center, Department of Haematology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

  https://orcid.org/0000-0001-6414-2671

  ⨯
• Simone Postma,

  Roles Data curation, Project administration, Validation, Writing – review & editing

  Affiliation Department of Haematology, University Medical Center Groningen, Groningen, The Netherlands

  ⨯
• Marit G. A. van Vonderen,

  Roles Data curation, Investigation, Project administration, Writing – review & editing

  Affiliation Department of Internal Medicine, Medical Center Leeuwarden, Leeuwarden, The Netherlands

  ⨯
• Djura P. Piersma,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Internal Medicine, Medisch Spectrum Twente, Enschede, The Netherlands

  ⨯
• Douwe Postma,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Internal Medicine, University Medical Center Groningen, Groningen, The Netherlands

  https://orcid.org/0000-0002-0675-8459

  ⨯
• Maarten van den Berge,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Pulmonology, University Medical Center Groningen, Groningen, The Netherlands

  ⨯
• Eefje Jong,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Infectious Diseases, Meander MC, Amersfoort, The Netherlands

  ⨯
• Marten de Vries,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Pulmonology, Tjongerschans Hospital, Heerenveen, The Netherlands

  ⨯
• Leonie van der Burg,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Internal Medicine, Antonius Hospital Sneek, Sneek, The Netherlands

  ⨯
• Dennis Huugen,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Internal Medicine, Deventer Hospital, Deventer, The Netherlands

  ⨯
• Marjolein van der Poel,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Internal Medicine, Maastricht University Medical Centre+, Maastricht, The Netherlands

  ⨯
• Linda M. Kampschreur,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Internal Medicine, Medical Center Leeuwarden, Leeuwarden, The Netherlands

  ⨯
• Marcel Nijland,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Haematology, University Medical Center Groningen, Groningen, The Netherlands

  ⨯
• Jaap H. Strijbos,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Pulmonology, Nij Smellinghe Hospital, Drachten, The Netherlands

  ⨯
• Menno Tamminga,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Pulmonology, University Medical Center Groningen, Groningen, The Netherlands

  https://orcid.org/0000-0001-6508-2623

  ⨯
• Pim G. N. J. Mutsaers,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Haematology, Erasmus Medical Center, Rotterdam, The Netherlands

  ⨯
• Suzanne Schol-Gelok,

  Roles Investigation, Writing – review & editing

  Affiliations Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands, Department of Emergency Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands

  ⨯
• Margriet Dijkstra-Tiekstra,

  Roles Data curation, Project administration, Validation, Writing – review & editing

  Affiliation Department of Haematology, University Medical Center Groningen, Groningen, The Netherlands

  ⨯
• Grigory Sidorenkov,

  Roles Conceptualization, Data curation, Writing – review & editing

  Affiliation Department of Epidemiology, University Medical Center Groningen, Groningen, The Netherlands

  ⨯
• Julien Vincenten,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Pulmonology, Albert Schweitzer Hospital, Dordrecht, The Netherlands

  ⨯
• Wouter H. van Geffen,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Pulmonology, Medical Center Leeuwarden, Leeuwarden, The Netherlands

  ⨯
• Marjolein Knoester,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliation Department of Medical Microbiology, University Medical Center Groningen, Groningen, The Netherlands

  ⨯
• Jos Kosterink,

  Roles Conceptualization, Investigation, Project administration, Writing – review & editing

  Affiliation Pharmacy, University Medical Center Groningen, Groningen, The Netherlands

  ⨯
• Reinold Gans,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliation Department of Internal Medicine, University Medical Center Groningen, Groningen, The Netherlands

  ⨯
• Coen Stegeman,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Internal Medicine, University Medical Center Groningen, Groningen, The Netherlands

  ⨯
• Gerwin Huls,

  Roles Conceptualization, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Haematology, University Medical Center Groningen, Groningen, The Netherlands

  ⨯
•  [ ... ],
• Tom van Meerten

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Haematology, University Medical Center Groningen, Groningen, The Netherlands

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