Intranasal administration of abatacept enhances IL-35⁺ and IL-10⁺ producing Bregs in lung tissues of ovalbumin-sensitized asthmatic mice model

• Maha Fahad Alenazy,

  Roles Conceptualization, Data curation, Methodology, Writing – review & editing

  Affiliations Department of Pediatrics, Immunology Research Lab, College of Medicine, King Saud University, Riyadh, Saudi Arabia, Department of Physiology, College of Medicine, King Saud University, Riyadh, Saudi Arabia

  ⨯
• Fatemeh Saheb Sharif-Askari,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Writing – original draft, Writing – review & editing

  Affiliation Sharjah Institute of Medical Research, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates

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• Mohammed S. El-Wetidy,

  Roles Data curation, Methodology

  Affiliation College of Medicine Research Center, King Saud University, Riyadh, Saudi Arabia

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• Narjes Saheb Sharif-Askari,

  Roles Formal analysis, Writing – review & editing

  Affiliation Sharjah Institute of Medical Research, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates

  ⨯
• Ibrahim Yaseen Hachim,

  Roles Formal analysis, Writing – review & editing

  Affiliations Sharjah Institute of Medical Research, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates, Department of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates

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• Mohammad-Hani Temsah,

  Roles Writing – review & editing

  Affiliation Department of Pediatrics, Immunology Research Lab, College of Medicine, King Saud University, Riyadh, Saudi Arabia

  https://orcid.org/0000-0002-4389-9322

  ⨯
• Basema Saddik,

  Roles Writing – review & editing

  Affiliations Sharjah Institute of Medical Research, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates, Department of Family and Community Medicine, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates

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• Roua Al-Kufaidy,

  Roles Writing – review & editing

  Affiliation Prince Naif Center for Immunology Research and Asthma Research Chair, College of Medicine, King Saud University, Riyadh, Saudi Arabia

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• Maha A. Omair,

  Roles Writing – review & editing

  Affiliation Department of Statistics and Operations Research, College of Science, King Saud University, Riyadh, Saudi Arabia

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• Yasser A. Alshawakir,

  Roles Data curation

  Affiliation Experimental Surgery and Animal Lab, College of Medicine, King Saud University, Riyadh, Saudi Arabia

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• Amany Adulgadel Fathaddin,

  Roles Data curation

  Affiliations Department of Pathology, College of Medicine, King Saud University, Riyadh, Saudi Arabia, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia

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• Suad Hannawi,

  Roles Writing – review & editing

  Affiliation Department of Medicine, Ministry of Health and Prevention, Dubai, United Arab Emirates

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• Qutayba Hamid,

  Roles Writing – review & editing

  Affiliations Sharjah Institute of Medical Research, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates, Department of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates, Meakins-Christie Laboratories, Research Institute of the McGill University Health Center, Montreal, Quebec, Canada

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• Mohammed A. Omair ,

  Contributed equally to this work with: Mohammed A. Omair, Saleh Al-Muhsen, Rabih Halwani

  Roles Writing – review & editing

  Affiliation Department of Medicine, Rheumatology Unit, College of Medicine, King Saud University, Riyadh, Saudi Arabia

  ⨯
• Saleh Al-Muhsen ,

  Contributed equally to this work with: Mohammed A. Omair, Saleh Al-Muhsen, Rabih Halwani

  Roles Conceptualization, Writing – review & editing

  Affiliations Department of Pediatrics, Immunology Research Lab, College of Medicine, King Saud University, Riyadh, Saudi Arabia, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia, Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia

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•  [ ... ],
• Rabih Halwani

  Contributed equally to this work with: Mohammed A. Omair, Saleh Al-Muhsen, Rabih Halwani

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: rhalwani@sharjah.ac.ae

  Affiliations Department of Pediatrics, Immunology Research Lab, College of Medicine, King Saud University, Riyadh, Saudi Arabia, Sharjah Institute of Medical Research, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates, Department of Clinical Sciences, College of Medicine, University of Sharjah, Sharjah, United Arab Emirates

  https://orcid.org/0000-0002-6516-7771

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