Low antithrombin levels are associated with low risk of cardiovascular death but are a risk factor for cancer mortality

• Licia Iacoviello,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Supervision, Visualization, Writing – review & editing

  Affiliations Department of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Italy, Research Center in Epidemiology and Preventive Medicine (EPIMED), Department of Medicine and Surgery, University of Insubria, Varese, Italy

  ⨯
• Romy de Laat-Kremers ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: r.delaat@thrombin.com

  Affiliation Department of Data Analysis and Artificial Intelligence, Synapse Research Institute, Maastricht, The Netherlands

  https://orcid.org/0000-0001-6526-0338

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• Simona Costanzo,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Italy

  https://orcid.org/0000-0003-4569-1186

  ⨯
• Qiuting Yan,

  Roles Data curation, Project administration, Writing – review & editing

  Affiliations Department of Functional Coagulation, Synapse Research Institute, Maastricht, The Netherlands, Department of Biochemistry, CARIM, Maastricht University, Maastricht, The Netherlands

  ⨯
• Augusto Di Castelnuovo,

  Roles Supervision, Writing – review & editing

  Affiliation Mediterranea Cardiocentro, Napoli, Italy

  ⨯
• Lisa van der Vorm,

  Roles Data curation, Project administration, Writing – review & editing

  Affiliations Department of Functional Coagulation, Synapse Research Institute, Maastricht, The Netherlands, Department of Biochemistry, CARIM, Maastricht University, Maastricht, The Netherlands

  ⨯
• Amalia De Curtis,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Italy

  ⨯
• Marisa Ninivaggi,

  Roles Data curation, Supervision, Writing – review & editing

  Affiliation Department of Functional Coagulation, Synapse Research Institute, Maastricht, The Netherlands

  ⨯
• Chiara Cerletti,

  Roles Writing – review & editing

  Affiliation Department of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Italy

  ⨯
• Maria Benedetta Donati,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Department of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Italy

  ⨯
• Bas de Laat,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Data Analysis and Artificial Intelligence, Synapse Research Institute, Maastricht, The Netherlands, Department of Functional Coagulation, Synapse Research Institute, Maastricht, The Netherlands, Department of Biochemistry, CARIM, Maastricht University, Maastricht, The Netherlands

  ⨯
• on behalf of the Moli-sani Investigators

  ¶Moli-sani Study Investigators are listed in the S1 Appendix.

  ⨯