Antimicrobial effects of inhaled sphingosine against Pseudomonas aeruginosa in isolated ventilated and perfused pig lungs

• Henning Carstens ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Writing – original draft

  * E-mail: h.carstens@uke.de

  Affiliations Department of Thoracic and Cardiovascular Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany, Cardiac Surgery for Congenital Heart Disease, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

  https://orcid.org/0000-0002-9472-1663

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• Katharina Kalka,

  Roles Data curation, Formal analysis, Project administration, Resources, Writing – review & editing

  Affiliation Department of Thoracic and Cardiovascular Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

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• Rabea Verhaegh,

  Roles Formal analysis, Resources

  Affiliation Institute of Molecular Biology, University of Duisburg-Essen, Essen, Germany

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• Fabian Schumacher,

  Roles Methodology

  Affiliation Institute of Pharmacy, Freie Universität Berlin, Berlin, Germany

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• Matthias Soddemann,

  Roles Methodology

  Affiliation Institute of Molecular Biology, University of Duisburg-Essen, Essen, Germany

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• Barbara Wilker,

  Roles Methodology

  Affiliation Institute of Molecular Biology, University of Duisburg-Essen, Essen, Germany

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• Simone Keitsch,

  Roles Methodology

  Affiliation Institute of Molecular Biology, University of Duisburg-Essen, Essen, Germany

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• Carolin Sehl,

  Roles Methodology

  Affiliation Institute of Molecular Biology, University of Duisburg-Essen, Essen, Germany

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• Burkhard Kleuser,

  Roles Methodology, Writing – review & editing

  Affiliation Institute of Pharmacy, Freie Universität Berlin, Berlin, Germany

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• Michael Hübler,

  Roles Writing – review & editing

  Affiliation Cardiac Surgery for Congenital Heart Disease, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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• Ursula Rauen,

  Roles Resources, Writing – review & editing

  Affiliation Institute of Biochemistry, University of Duisburg-Essen, Essen, Germany

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• Anne Katrin Becker,

  Roles Writing – review & editing

  Affiliation Institute of Molecular Biology, University of Duisburg-Essen, Essen, Germany

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• Achim Koch,

  Roles Writing – review & editing

  Affiliation Department of Thoracic and Cardiovascular Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

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• Erich Gulbins ,

  Contributed equally to this work with: Erich Gulbins, Markus Kamler

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliations Institute of Molecular Biology, University of Duisburg-Essen, Essen, Germany, Department of Surgery, University of Cincinnati, Medical School, Cincinnati, OH, United States of America

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• Markus Kamler

  Contributed equally to this work with: Erich Gulbins, Markus Kamler

  Roles Funding acquisition, Project administration, Writing – review & editing

  Affiliation Department of Thoracic and Cardiovascular Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

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