Characterization of a KDM5 small molecule inhibitor with antiviral activity against hepatitis B virus

• Sarah A. Gilmore,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Current address: Allovir, Waltham, Massachusetts, United States America

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

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• Danny Tam,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

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• Tara L. Cheung,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Chelsea Snyder,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Supervision

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

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• Julie Farand,

  Roles Conceptualization, Data curation, Formal analysis, Investigation

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

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• Ryan Dick,

  Roles Conceptualization, Data curation, Formal analysis, Investigation

  Current address: Maze Therapeutics, South San Francisco, California, United States America

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Mike Matles,

  Roles Data curation, Investigation

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Joy Y. Feng,

  Roles Formal analysis, Investigation

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Ricardo Ramirez,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Li Li,

  Roles Investigation, Methodology, Project administration

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Helen Yu,

  Roles Formal analysis, Investigation

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Yili Xu,

  Roles Formal analysis

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Dwight Barnes,

  Roles Data curation, Formal analysis

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Gregg Czerwieniec,

  Roles Formal analysis, Investigation

  Current address: Nektar Therapeutics, San Francisco, California, United States America

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Katherine M. Brendza,

  Roles Formal analysis, Investigation

  Current address: Nektar Therapeutics, San Francisco, California, United States America

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Todd C. Appleby,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Gabriel Birkus,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation

  Current address: Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czech Republic

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Madeleine Willkom,

  Roles Data curation, Formal analysis

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Tetsuya Kobayashi,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Eric Paoli,

  Roles Formal analysis, Investigation

  Current address: Verily Life Sciences, South San Francisco, California, United States America

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Marc Labelle ,

  Roles Conceptualization

  ¶† Deceased. M.L. passed away before the submission of the final version of this manuscript. U.S. accepts responsibility for the integrity and validity of the data collected and analyzed.

  Affiliation EpiTherapeutics ApS, Copenhagen, Denmark

  ⨯
• Thomas Boesen,

  Roles Conceptualization

  Affiliations EpiTherapeutics ApS, Copenhagen, Denmark, Novo Nordisk A/S, Bagsvaerd, Denmark

  ⨯
• Chin H. Tay,

  Roles Data curation, Formal analysis, Investigation

  Current address: Vir Biotechnology, San Francisco, California, United States America

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• William E. Delaney IV,

  Roles Conceptualization, Supervision

  Current address: Assembly Biosciences, South San Francisco, California, United States America

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Gregory T. Notte,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Validation, Visualization

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

  ⨯
• Uli Schmitz ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Writing – review & editing

  * E-mail: uli.schmitz@gilead.com

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

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•  [ ... ],
• Becket Feierbach

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Gilead Sciences, Inc., Foster City, California, United States America

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