Development of an aerosol intervention for COVID-19 disease: Tolerability of soluble ACE2 (APN01) administered via nebulizer

• Robert H. Shoemaker ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Robert.Shoemaker@nih.gov

  Affiliation Chemopreventive Agent Development Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Reynold A. Panettieri Jr.,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Rutgers Institute for Translational Medicine and Science, New Brunswick, New Jersey, United States of America

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• Steven K. Libutti,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Rutgers Cancer Institute, New Brunswick, New Jersey, United States of America

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• Howard S. Hochster,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Rutgers Cancer Institute, New Brunswick, New Jersey, United States of America

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• Norman R. Watts,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Protein Expression Laboratory, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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• Paul T. Wingfield,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Protein Expression Laboratory, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  https://orcid.org/0000-0002-9515-4752

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• Philipp Starkl,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria

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• Lisabeth Pimenov,

  Roles Conceptualization, Data curation, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria

  https://orcid.org/0000-0002-5154-4070

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• Riem Gawish,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria

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• Anastasiya Hladik,

  Roles Conceptualization, Data curation, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria

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• Sylvia Knapp,

  Roles Conceptualization, Data curation, Formal analysis, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Medicine I, Laboratory of Infection Biology, Medical University of Vienna, Vienna, Austria

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• Daniel Boring,

  Roles Conceptualization, Data curation, Formal analysis, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Chemopreventive Agent Development Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Jonathan M. White,

  Roles Conceptualization, Data curation, Formal analysis, Supervision, Writing – original draft, Writing – review & editing

  Affiliation MRIGlobal, Kansas City, Missouri, United States of America

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• Quentin Lawrence,

  Roles Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation MRIGlobal, Kansas City, Missouri, United States of America

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• Jeremy Boone,

  Roles Data curation, Formal analysis, Investigation

  Affiliation MRIGlobal, Kansas City, Missouri, United States of America

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• Jason D. Marshall,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Cancer ImmunoPrevention Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

  https://orcid.org/0000-0002-7864-803X

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• Rebecca L. Matthews,

  Roles Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Cancer ImmunoPrevention Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

  https://orcid.org/0000-0001-7420-9374

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• Brian D. Cholewa,

  Roles Conceptualization, Formal analysis, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Chemopreventive Agent Development Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Jeffrey W. Richig,

  Roles Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation IIT Research Institute, Chicago, Illinois, United States of America

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• Ben T. Chen,

  Roles Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation IIT Research Institute, Chicago, Illinois, United States of America

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• David L. McCormick,

  Roles Conceptualization, Data curation, Formal analysis, Supervision, Writing – original draft, Writing – review & editing

  Affiliation IIT Research Institute, Chicago, Illinois, United States of America

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• Romana Gugensberger,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Apeiron Biologics AG, Campus-Vienna-Biocenter 5, Vienna, Austria

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• Sonja Höller,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Apeiron Biologics AG, Campus-Vienna-Biocenter 5, Vienna, Austria

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• Josef M. Penninger,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliations Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna, Austria, Department of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada

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•  [ ... ],
• Gerald Wirnsberger

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Apeiron Biologics AG, Campus-Vienna-Biocenter 5, Vienna, Austria

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