Polygenic score for Alzheimer’s disease identifies differential atrophy in hippocampal subfield volumes

• Balaji Kannappan ,

  Contributed equally to this work with: Balaji Kannappan, Tamil Iniyan Gunasekaran

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

  Affiliations Gwangju Alzheimer’s & Related Dementia Cohort Research Center, Chosun University, Gwangju, Republic of Korea, Department of Biomedical Science, Chosun University, Gwangju, Republic of Korea

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• Tamil Iniyan Gunasekaran ,

  Contributed equally to this work with: Balaji Kannappan, Tamil Iniyan Gunasekaran

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

  Affiliations Gwangju Alzheimer’s & Related Dementia Cohort Research Center, Chosun University, Gwangju, Republic of Korea, Department of Biomedical Science, Chosun University, Gwangju, Republic of Korea

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• Jan te Nijenhuis ,

  Roles Project administration, Supervision, Writing – review & editing

  * E-mail: JanteNijenhuis@planet.nl (JN); leekho@chosun.ac.kr (KHL)

  Affiliations Gwangju Alzheimer’s & Related Dementia Cohort Research Center, Chosun University, Gwangju, Republic of Korea, Department of Biomedical Science, Chosun University, Gwangju, Republic of Korea

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• Muthu Gopal,

  Roles Resources, Writing – review & editing

  Affiliation Health Systems Research & MRHRU, ICMR-National Institute of Epidemiology, Tirunelveli, Tamil Nadu, India

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• Deepika Velusami,

  Roles Resources, Writing – review & editing

  Affiliation Department of Physiology, Sri Manakula Vinayagar Medical College and Hospital, Puducherry, Tamil Nadu, India

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• Gugan Kothandan,

  Roles Resources, Writing – review & editing

  Affiliation Biopolymer Modeling and Protein Chemistry Laboratory, Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Chennai, Tamil Nadu, India

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• Kun Ho Lee ,

  Roles Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: JanteNijenhuis@planet.nl (JN); leekho@chosun.ac.kr (KHL)

  Affiliations Gwangju Alzheimer’s & Related Dementia Cohort Research Center, Chosun University, Gwangju, Republic of Korea, Department of Biomedical Science, Chosun University, Gwangju, Republic of Korea, Korea Brain Research Institute, Daegu, Republic of Korea

  https://orcid.org/0000-0003-4144-8162

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• for the Alzheimer’s Disease Neuroimaging Initiative

  ¶Membership of the Alzheimer’s Disease Neuroimaging Initiative (ADNI) is listed in the Acknowledgments.

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