Comparison of serum and plasma as a source of blood extracellular vesicles: Increased levels of platelet-derived particles in serum extracellular vesicle fractions alter content profiles from plasma extracellular vesicle fractions

• Xiaoman Zhang,

  Roles Formal analysis, Investigation, Methodology, Validation, Writing – original draft

  Affiliations Department of Neurotherapeutics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, Department of Neurology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan

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• Toshihide Takeuchi ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: takeuchi@med.kindai.ac.jp (TT); yoshi.nagai@med.kindai.ac.jp (YN)

  Affiliations Department of Neurotherapeutics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, Life Science Research Institute, Kindai University, Osaka-Sayama, Osaka, Japan, PRESTO, Japan Science and Technology Agency (JST), Osaka, Japan

  https://orcid.org/0000-0002-6236-8009

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• Akiko Takeda,

  Roles Investigation, Methodology

  Affiliations Department of Neurotherapeutics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, Department of Neurology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan

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• Hideki Mochizuki,

  Roles Funding acquisition, Supervision

  Affiliation Department of Neurology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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• Yoshitaka Nagai

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: takeuchi@med.kindai.ac.jp (TT); yoshi.nagai@med.kindai.ac.jp (YN)

  Affiliations Department of Neurotherapeutics, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, Department of Neurology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan, Department of Neurology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

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