Granzyme K initiates IL-6 and IL-8 release from epithelial cells by activating protease-activated receptor 2

• Dion Kaiserman ,

  Roles Data curation, Formal analysis, Investigation, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: dion.kaiserman@monash.edu

  Affiliation Department of Biochemistry & Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia

  https://orcid.org/0000-0003-2692-030X

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• Peishen Zhao,

  Roles Formal analysis, Investigation, Methodology, Resources, Writing – original draft, Writing – review & editing

  Affiliations Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia, Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, Parkville, VIC, Australia

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• Caitlin Lorraine Rowe,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Biochemistry & Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia

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• Andrea Leong,

  Roles Investigation

  Affiliations Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia, Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, Parkville, VIC, Australia

  https://orcid.org/0000-0002-2423-2012

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• Nicholas Barlow,

  Roles Data curation, Investigation, Methodology, Resources, Writing – original draft, Writing – review & editing

  Affiliation Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia

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• Lars Thomas Joeckel,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Biochemistry & Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia

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• Corinne Hitchen,

  Roles Resources, Writing – review & editing

  Affiliation Department of Biochemistry & Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia

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• Sarah Elizabeth Stewart,

  Roles Resources, Writing – review & editing

  Current address: Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne VIC, Australia

  Affiliation Department of Biochemistry & Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia

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• Morley D. Hollenberg,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Department of Physiology & Pharmacology, Department of Medicine, University of Calgary, Calgary AB, Canada

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• Nigel Bunnett,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Department of Molecular Pathobiology, Department of Neuroscience and Physiology, Neuroscience Institute, New York University, New York, NY, United States of America

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• Andreas Suhrbier,

  Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing

  Affiliations QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia, Australian Infectious Disease Research Centre, University of Queensland, Brisbane, QLD, Australia

  https://orcid.org/0000-0001-8986-9025

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• Phillip Ian Bird

  Roles Conceptualization, Investigation, Methodology, Resources, Writing – review & editing

  Affiliation Department of Biochemistry & Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia

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