Performance estimation of two in-house ELISA assays for COVID-19 surveillance through the combined detection of anti-SARS-CoV-2 IgA, IgM, and IgG immunoglobulin isotypes

• Alfredo Ramírez-Reveco ,

  Contributed equally to this work with: Alfredo Ramírez-Reveco, Cristóbal C. Verdugo

  Roles Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliation Instituto de Ciencia Animal, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia, Chile

  https://orcid.org/0000-0003-4782-4261

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• Gerardo Velásquez ,

  Roles Data curation, Formal analysis

  ¶‡ GV, CA and GN also contributed equally to this work.

  Affiliations Instituto de Ciencia Animal, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia, Chile, Laboratorio de Biología Molecular, Hospital Base de Valdivia (HBV), Valdivia, Chile

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• Christopher Aros ,

  Roles Data curation, Formal analysis

  ¶‡ GV, CA and GN also contributed equally to this work.

  Affiliations Instituto de Ciencia Animal, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia, Chile, Escuela de Bioquímica, Facultad de Ciencias, Universidad Austral de Chile, Valdivia, Chile

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• Gabriela Navarrete ,

  Roles Data curation, Formal analysis

  ¶‡ GV, CA and GN also contributed equally to this work.

  Affiliations Instituto de Ciencia Animal, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia, Chile, Escuela de Bioquímica, Facultad de Ciencias, Universidad Austral de Chile, Valdivia, Chile

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• Franz Villarroel-Espíndola,

  Roles Conceptualization, Writing – review & editing

  Affiliation Laboratorio Medicina Traslacional, Instituto Oncológico Fundación Arturo López Pérez, Santiago, Chile

  ⨯
• Maritza Navarrete,

  Roles Conceptualization, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliation Laboratorio de Biología Molecular, Hospital Base de Valdivia (HBV), Valdivia, Chile

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• Alberto Fica,

  Roles Conceptualization, Methodology

  Affiliation Sub Departamento de Medicina, Hospital Base Valdivia; Instituto Medicina, Facultad de Medicina, Universidad Austral de Chile, Valdivia, Chile

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• Anita Plaza,

  Roles Formal analysis

  Affiliation Center for the Surveillance and Evolution of Infectious Diseases (CSEID), Universidad Austral de Chile, Valdivia, Chile

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• Natalia Castro,

  Roles Data curation, Project administration, Supervision

  Affiliation Center for the Surveillance and Evolution of Infectious Diseases (CSEID), Universidad Austral de Chile, Valdivia, Chile

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• Claudio Verdugo,

  Roles Writing – original draft

  Affiliations Center for the Surveillance and Evolution of Infectious Diseases (CSEID), Universidad Austral de Chile, Valdivia, Chile, Instituto de Patología Animal, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia, Chile

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• Gerardo Acosta-Jamett,

  Roles Conceptualization, Methodology, Writing – original draft

  Affiliations Center for the Surveillance and Evolution of Infectious Diseases (CSEID), Universidad Austral de Chile, Valdivia, Chile, Instituto de Medicina Preventiva, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia, Chile

  https://orcid.org/0000-0002-9645-3551

  ⨯
• Cristóbal C. Verdugo

  Contributed equally to this work with: Alfredo Ramírez-Reveco, Cristóbal C. Verdugo

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: cristobal.verdugo@uach.cl

  Affiliations Center for the Surveillance and Evolution of Infectious Diseases (CSEID), Universidad Austral de Chile, Valdivia, Chile, Instituto de Medicina Preventiva, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia, Chile

  https://orcid.org/0000-0002-8418-4219

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