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Open Access
Peer-reviewed
Research Article
An intensity-based post-processing tool for 3D instance segmentation of organelles in soft X-ray tomograms
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Angdi Li,
Roles Conceptualization, Formal analysis, Methodology, Project administration, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliations iHuman Institute, ShanghaiTech University, Shanghai, China, School of Life Science and Technology, ShanghaiTech University, Shanghai, China, University of Chinese Academy of Sciences, Beijing, China
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Shuning Zhang,
Roles Formal analysis, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliations iHuman Institute, ShanghaiTech University, Shanghai, China, School of Life Science and Technology, ShanghaiTech University, Shanghai, China, University of Chinese Academy of Sciences, Beijing, China
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Valentina Loconte,
Roles Data curation, Funding acquisition, Resources, Writing – review & editing
Affiliations iHuman Institute, ShanghaiTech University, Shanghai, China, School of Life Science and Technology, ShanghaiTech University, Shanghai, China
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Yan Liu,
Roles Funding acquisition, Validation, Writing – review & editing
Affiliations iHuman Institute, ShanghaiTech University, Shanghai, China, School of Life Science and Technology, ShanghaiTech University, Shanghai, China
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Axel Ekman,
Roles Data curation, Methodology, Validation
Affiliations Department of Anatomy, University of California San Francisco, San Francisco, CA, United States of America, Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, United States of America
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Garth J. Thompson,
Roles Methodology, Supervision, Writing – review & editing
Affiliation iHuman Institute, ShanghaiTech University, Shanghai, China
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Andrej Sali,
Roles Conceptualization, Methodology, Supervision, Visualization, Writing – review & editing
Affiliation California Institute for Quantitative Biosciences, Department of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA, United States of America
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Raymond C. Stevens,
Roles Data curation, Supervision, Writing – review & editing
Affiliations iHuman Institute, ShanghaiTech University, Shanghai, China, School of Life Science and Technology, ShanghaiTech University, Shanghai, China, Department of Biological Sciences, Bridge Institute, University of Southern California, Los Angeles, CA, United States of America, Department of Chemistry, Bridge Institute, University of Southern California, Los Angeles, CA, United States of America
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Kate White ,
Roles Data curation, Supervision, Writing – review & editing
* E-mail: katewhit@usc.edu (KW); jsingla@bt.iitr.ac.in (JS); sunlp@shanghaitech.edu.cn (LS)
Affiliation Department of Chemistry, Bridge Institute, University of Southern California, Los Angeles, CA, United States of America
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Jitin Singla ,
Roles Methodology, Visualization, Writing – review & editing
* E-mail: katewhit@usc.edu (KW); jsingla@bt.iitr.ac.in (JS); sunlp@shanghaitech.edu.cn (LS)
Affiliation Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India
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Liping Sun
Roles Conceptualization, Project administration, Resources, Supervision, Writing – review & editing
* E-mail: katewhit@usc.edu (KW); jsingla@bt.iitr.ac.in (JS); sunlp@shanghaitech.edu.cn (LS)
Affiliations iHuman Institute, ShanghaiTech University, Shanghai, China, School of Life Science and Technology, ShanghaiTech University, Shanghai, China
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An intensity-based post-processing tool for 3D instance segmentation of organelles in soft X-ray tomograms
- Angdi Li,
- Shuning Zhang,
- Valentina Loconte,
- Yan Liu,
- Axel Ekman,
- Garth J. Thompson,
- Andrej Sali,
- Raymond C. Stevens,
- Kate White,
- Jitin Singla
- Published: September 1, 2022
- https://doi.org/10.1371/journal.pone.0269887