Threshold of increase in oxygen demand to predict mechanical ventilation use in novel coronavirus disease 2019: A retrospective cohort study incorporating restricted cubic spline regression

Ryo Yamamoto; Ryo Takemura; Asako Yamamoto; Kazuki Matsumura; Daiki Kaito; Koichiro Homma; Michihiko Wada; Junichi Sasaki; on behalf of Keio Donner Project

doi:10.1371/journal.pone.0269876

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Open Access

Peer-reviewed

Research Article

Threshold of increase in oxygen demand to predict mechanical ventilation use in novel coronavirus disease 2019: A retrospective cohort study incorporating restricted cubic spline regression

Ryo Yamamoto ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

* E-mail: ryo.yamamoto@gmail.com

Affiliation Department of Emergency and Critical Care Medicine, Keio University School of Medicine, Tokyo, Japan

https://orcid.org/0000-0001-8772-9600

⨯
Ryo Takemura,

Roles Conceptualization, Data curation, Formal analysis, Writing – review & editing

Affiliation Clinical and Translational Research Center, Keio University Hospital, Tokyo, Japan

https://orcid.org/0000-0002-3733-7411

⨯
Asako Yamamoto,

Roles Data curation, Formal analysis, Project administration, Writing – review & editing

Affiliation Clinical and Translational Research Center, Keio University Hospital, Tokyo, Japan
⨯
Kazuki Matsumura,

Roles Validation, Writing – review & editing

Affiliation Department of Emergency and Critical Care Medicine, Keio University School of Medicine, Tokyo, Japan
⨯
Daiki Kaito,

Roles Conceptualization, Validation, Writing – review & editing

Affiliation Department of Emergency and Critical Care Medicine, Keio University School of Medicine, Tokyo, Japan
⨯
Koichiro Homma,

Roles Conceptualization, Supervision, Validation, Writing – review & editing

Affiliation Department of Emergency and Critical Care Medicine, Keio University School of Medicine, Tokyo, Japan
⨯
Michihiko Wada,

Roles Conceptualization, Data curation, Methodology, Writing – review & editing

Affiliation Clinical and Translational Research Center, Keio University Hospital, Tokyo, Japan
⨯
Junichi Sasaki,

Roles Supervision, Validation, Writing – review & editing

Affiliation Department of Emergency and Critical Care Medicine, Keio University School of Medicine, Tokyo, Japan

https://orcid.org/0000-0002-5190-8524

⨯
on behalf of Keio Donner Project

¶Membership of the Keio Donner Project is listed in the Acknowledgments.
⨯

Threshold of increase in oxygen demand to predict mechanical ventilation use in novel coronavirus disease 2019: A retrospective cohort study incorporating restricted cubic spline regression

Ryo Yamamoto,
Ryo Takemura,
Asako Yamamoto,
Kazuki Matsumura,
Daiki Kaito,
Koichiro Homma,
Michihiko Wada,
Junichi Sasaki,
on behalf of Keio Donner Project

Published: July 14, 2022
https://doi.org/10.1371/journal.pone.0269876

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