Nrf2 deficiency causes hepatocyte dedifferentiation and reduced albumin production in an experimental extrahepatic cholestasis model

• Guo-Ying Wang,

  Roles Data curation, Formal analysis, Methodology, Validation, Visualization, Writing – review & editing

  Affiliations Department of Biology, Center for Developmental and Regenerative Biology, School of Science, Indiana University-Purdue University Indianapolis, Indianapolis, IN, United States of America, Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China, Department of Hepatic Surgery and Liver Transplantation Center, The Third Affiliated Hospital, Sun Yet-Sen University, Guangdong, China

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• Veronica Garcia,

  Roles Data curation, Formal analysis, Investigation, Validation

  Affiliation Department of Biology, Center for Developmental and Regenerative Biology, School of Science, Indiana University-Purdue University Indianapolis, Indianapolis, IN, United States of America

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• Joonyong Lee,

  Roles Data curation, Formal analysis, Methodology, Validation

  Affiliation Department of Biology, Center for Developmental and Regenerative Biology, School of Science, Indiana University-Purdue University Indianapolis, Indianapolis, IN, United States of America

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• Jennifer Yanum,

  Roles Data curation, Formal analysis, Validation

  Affiliation Department of Biology, Center for Developmental and Regenerative Biology, School of Science, Indiana University-Purdue University Indianapolis, Indianapolis, IN, United States of America

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• Jingmei Lin,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliation Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, United States of America

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• Huaizhou Jiang ,

  Roles Conceptualization, Data curation, Investigation, Methodology, Validation, Writing – original draft

  * E-mail: huazhou@iu.edu (HJ); gdai@iupui.edu (GD)

  Affiliations Department of Biology, Center for Developmental and Regenerative Biology, School of Science, Indiana University-Purdue University Indianapolis, Indianapolis, IN, United States of America, School of Traditional Chinese Medicine, Anhui University of Chinese Medicine, Anhui, China

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• Guoli Dai

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: huazhou@iu.edu (HJ); gdai@iupui.edu (GD)

  Affiliation Department of Biology, Center for Developmental and Regenerative Biology, School of Science, Indiana University-Purdue University Indianapolis, Indianapolis, IN, United States of America

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