Investigating CRISPR/Cas9 gene drive for production of disease-preventing prion gene alleles

• Andrew R. Castle,

  Roles Conceptualization, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada

  https://orcid.org/0000-0003-2590-9555

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• Serene Wohlgemuth,

  Roles Formal analysis, Investigation, Visualization, Writing – review & editing

  Affiliations Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada

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• Luis Arce,

  Roles Investigation, Writing – review & editing

  Affiliations Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada, Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada

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• David Westaway

  Roles Conceptualization, Funding acquisition, Project administration, Visualization, Writing – review & editing

  * E-mail: david.westaway@ualberta.ca

  Affiliations Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Alberta, Canada, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada, Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada

  https://orcid.org/0000-0003-1928-4616

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