Mucosal immunity of mannose-modified chitosan microspheres loaded with the nontyepable Haemophilus influenzae outer membrane protein P6 in BALB/c mice

Yushuai Ma; Ying Zhao; Rui Chen; Wanru Sun; Yanxia Zhang; Haixia Qiao; Yueli Chang; Shaoping Kang; Yutuo Zhang

doi:10.1371/journal.pone.0269153

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Open Access

Peer-reviewed

Research Article

Mucosal immunity of mannose-modified chitosan microspheres loaded with the nontyepable Haemophilus influenzae outer membrane protein P6 in BALB/c mice

Yushuai Ma ,

Contributed equally to this work with: Yushuai Ma, Ying Zhao

Roles Conceptualization, Investigation, Methodology, Project administration, Resources, Software, Visualization, Writing – original draft

Affiliation Institute of Pathogen Biology and Immunology, Hebei North University, Zhangjiakou, Hebei Province, China
⨯
Ying Zhao ,

Contributed equally to this work with: Yushuai Ma, Ying Zhao

Roles Data curation, Methodology, Resources, Software, Visualization

Affiliation Institute of Pathogen Biology and Immunology, Hebei North University, Zhangjiakou, Hebei Province, China
⨯
Rui Chen,

Roles Methodology

Affiliation Institute of Pathogen Biology and Immunology, Hebei North University, Zhangjiakou, Hebei Province, China
⨯
Wanru Sun,

Roles Software

Affiliation Institute of Pathogen Biology and Immunology, Hebei North University, Zhangjiakou, Hebei Province, China
⨯
Yanxia Zhang,

Roles Resources

Affiliation Department of Microbiology, Hebei North University, Zhangjiakou, Hebei Province, China
⨯
Haixia Qiao,

Roles Resources

Affiliation Department of Microbiology, Hebei North University, Zhangjiakou, Hebei Province, China
⨯
Yueli Chang,

Roles Software

Affiliation Department of Microbiology, Hebei North University, Zhangjiakou, Hebei Province, China
⨯
Shaoping Kang,

Roles Software

Affiliation Department of Immunology, Hebei North University, Zhangjiakou, Hebei Province, China
⨯
Yutuo Zhang

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Writing – review & editing

* E-mail: yvtuozhang@163.com

Affiliation Department of Microbiology, Hebei North University, Zhangjiakou, Hebei Province, China
⨯

Mucosal immunity of mannose-modified chitosan microspheres loaded with the nontyepable Haemophilus influenzae outer membrane protein P6 in BALB/c mice

Yushuai Ma,
Ying Zhao,
Rui Chen,
Wanru Sun,
Yanxia Zhang,
Haixia Qiao,
Yueli Chang,
Shaoping Kang,
Yutuo Zhang

Published: June 10, 2022
https://doi.org/10.1371/journal.pone.0269153

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