GPC1 promotes the growth and migration of colorectal cancer cells through regulating the TGF-β1/SMAD2 signaling pathway

Fei Lu; Shuran Chen; Weijun Shi; Xu Su; Huazhang Wu; Mulin Liu

doi:10.1371/journal.pone.0269094

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Open Access

Peer-reviewed

Research Article

GPC1 promotes the growth and migration of colorectal cancer cells through regulating the TGF-β1/SMAD2 signaling pathway

Fei Lu,

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Gastrointestinal Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, China
⨯
Shuran Chen,

Roles Data curation, Investigation, Validation

Affiliation Gastrointestinal Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, China
⨯
Weijun Shi,

Roles Formal analysis, Writing – original draft, Writing – review & editing

Affiliation Gastrointestinal Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, China
⨯
Xu Su,

Roles Data curation, Investigation, Validation

Affiliation School of Life Science, Anhui Province Key Laboratory of Translational Cancer Research, Bengbu Medical College, Bengbu, China
⨯
Huazhang Wu ,

Roles Conceptualization, Funding acquisition, Writing – original draft, Writing – review & editing

* E-mail: 1143274470@qq.com (HW); 2583375185@qq.com (ML)

Affiliation School of Life Science, Anhui Province Key Laboratory of Translational Cancer Research, Bengbu Medical College, Bengbu, China
⨯
Mulin Liu

Roles Conceptualization, Funding acquisition, Project administration, Writing – original draft, Writing – review & editing

* E-mail: 1143274470@qq.com (HW); 2583375185@qq.com (ML)

Affiliation Gastrointestinal Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, China

https://orcid.org/0000-0003-2655-5402

⨯

GPC1 promotes the growth and migration of colorectal cancer cells through regulating the TGF-β1/SMAD2 signaling pathway

Fei Lu,
Shuran Chen,
Weijun Shi,
Xu Su,
Huazhang Wu,
Mulin Liu

Published: June 7, 2022
https://doi.org/10.1371/journal.pone.0269094

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Colorectal cancer
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Apoptosis
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Transfection
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Gene expression
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Lung and intrathoracic tumors
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SW480 cells
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SMAD signaling
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Cell migration
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