Efficacy and safety of anakinra in adults presenting deteriorating respiratory symptoms from COVID-19: A randomized controlled trial

• Alexandra Audemard-Verger ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: a.audemard-verger@chu-tours.fr

  Affiliations Department of Internal Medicine and Clinical Immunology, CHRU Tours, Tours, France, University of Tours, Tours, France

  https://orcid.org/0000-0002-0226-5016

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• Amélie Le Gouge,

  Roles Conceptualization, Data curation, Formal analysis, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation INSERM CIC1415, CHRU Tours, Tours, France

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• Vincent Pestre,

  Roles Formal analysis, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Internal Medicine and Infectious Diseases, CH Avignon, Avignon, France

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• Johan Courjon,

  Roles Formal analysis, Funding acquisition, Software, Supervision

  Affiliation Department of Infectious Diseases, Université Côte d’Azur, CHU Nice, Nice, France

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• Vincent Langlois,

  Roles Funding acquisition, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Internal Medicine, CH du Havre, Le Havre, France

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• Marc-Olivier Vareil,

  Roles Conceptualization, Data curation, Formal analysis, Investigation

  Affiliation Department of Infectious Diseases, CH de Bayonne, Bayonne, France

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• Mathilde Devaux,

  Roles Data curation, Formal analysis

  Affiliation Department of Internal Medicine, CH de Poissy, Poissy, France

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• Boris Bienvenu,

  Roles Data curation, Formal analysis, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Internal Medicine, Hôpital Saint Joseph, Marseille, France

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• Vincent Leroy,

  Roles Data curation, Funding acquisition, Project administration, Resources

  Affiliation Department of Infectious Diseases, Clinique Tessier, Valenciennes, France

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• Radjiv Goulabchand,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation

  Affiliation Internal Medicine Department & Department of Infectious and Tropical Diseases, Nîmes University Hospital, University of Montpellier, Nîmes, France

  https://orcid.org/0000-0002-7328-4097

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• Léa Colombain,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation

  Affiliation Department of Infectious Diseases, CH de Perpignan, Perpignan, France

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• Adrien Bigot,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation

  Affiliation Department of Internal Medicine and Clinical Immunology, CHRU Tours, Tours, France

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• Thomas Guimard,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition

  Affiliation Department of Infectious Diseases, CH la Roche sur Yon, La Roche sur Yon, France

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• Youcef Douadi,

  Roles Conceptualization, Formal analysis, Methodology, Project administration

  Affiliation Department of Infectious Diseases, CH Saint Quentin, Saint Quentin, France

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• Geoffrey Urbanski,

  Roles Conceptualization, Formal analysis, Funding acquisition, Validation, Writing – original draft

  Affiliation Department of Internal Medicine and Clinical Immunology, CHU Angers, Angers France

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• Jean François Faucher,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation

  Affiliation Department of Infectious Diseases, CHU de Limoges, Limoges, France

  https://orcid.org/0000-0002-1629-1194

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• Laurence Maulin,

  Roles Conceptualization, Funding acquisition, Writing – original draft, Writing – review & editing

  Affiliation Department of Infectious Diseases, CH Aix en Provence, Aix en Provence, France

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• Bertrand Lioger,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition

  Affiliation Department of Internal Medicine, CH de Blois, Blois, France

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• Jean-Philippe Talarmin,

  Roles Formal analysis, Funding acquisition, Investigation

  Affiliation Department of Internal Medicine and Infectious Diseases, CH de Quimper, Quimper, France

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• Matthieu Groh,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation

  Affiliation Department of Internal Medicine, Hôpital Foch, Suresnes, France

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• Joseph Emmerich,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation

  Affiliation Department of Vascular Medicine, GH Saint Joseph and Université de Paris, INSERM CRESS 1153, Paris, France

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• Sophie Deriaz,

  Roles Data curation, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Internal Medicine and Clinical Immunology, CHRU Tours, Tours, France

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• Nicole Ferreira-Maldent,

  Roles Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft

  Affiliation Department of Internal Medicine and Clinical Immunology, CHRU Tours, Tours, France

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• Ann-Rose Cook,

  Roles Conceptualization, Formal analysis, Investigation, Project administration, Writing – original draft

  Affiliation Department of Internal Medicine and Clinical Immunology, CHRU Tours, Tours, France

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• Céline Lengellé,

  Roles Investigation, Methodology, Resources, Validation, Visualization

  Affiliation Clinical Research Vigilance Unit, CHRU Tours, Tours, France

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• Hélène Bourgoin,

  Roles Conceptualization, Funding acquisition, Software, Supervision, Validation

  Affiliation Department of Pharmacology, CHRU Tours, Tours, France

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• Arsène Mekinian,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Writing – review & editing

  Affiliation Department of Internal Medicine, Hôpital Saint Antoine, Sorbonne Université, Paris, France

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• Achille Aouba,

  Roles Data curation, Formal analysis, Methodology, Project administration

  Affiliation Department of Internal Medicine, CHU de Caen, Caen, France

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• François Maillot,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Validation

  Affiliations Department of Internal Medicine and Clinical Immunology, CHRU Tours, Tours, France, University of Tours, Tours, France

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•  [ ... ],
• Agnès Caille

  Roles Conceptualization, Data curation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Affiliations University of Tours, Tours, France, INSERM CIC1415, CHRU Tours, Tours, France

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