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Open Access
Peer-reviewed
Research Article
15-PGDH regulates hematopoietic and gastrointestinal fitness during aging
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Won Jin Ho ,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
¶‡ WJH and JNPS contributed equally to this work and served as co-first authors. SDM and ABD also contributed equally to this work and served as corresponding author.
Affiliations Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Medicine, and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America
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Julianne N. P. Smith ,
Roles Data curation, Investigation, Writing – review & editing
¶‡ WJH and JNPS contributed equally to this work and served as co-first authors. SDM and ABD also contributed equally to this work and served as corresponding author.
Affiliation Department of Medicine, and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America
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Young Soo Park,
Roles Formal analysis, Methodology
Affiliation Department of Medicine, and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America
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Matthew Hadiono,
Roles Investigation
Affiliation Department of Medicine, and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America
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Kelsey Christo,
Roles Investigation
Affiliation Department of Medicine, and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America
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Alvin Jogasuria,
Roles Investigation
Affiliation Department of Medicine, and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America
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Yongyou Zhang,
Roles Investigation
Affiliation Department of Medicine, and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America
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Alyssia V. Broncano,
Roles Investigation
Affiliation Department of Medicine, and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America
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Lakshmi Kasturi,
Roles Investigation
Affiliation Department of Medicine, and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America
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Dawn M. Dawson,
Roles Formal analysis
Affiliation Department of Medicine, and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America
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Stanton L. Gerson,
Roles Conceptualization, Formal analysis
Affiliations Department of Medicine, and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America, University Hospitals Seidman Cancer Center, Cleveland, Ohio, United States of America
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Sanford D. Markowitz ,
Roles Conceptualization, Supervision, Writing – review & editing
¶‡ WJH and JNPS contributed equally to this work and served as co-first authors. SDM and ABD also contributed equally to this work and served as corresponding author.
Affiliations Department of Medicine, and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America, University Hospitals Seidman Cancer Center, Cleveland, Ohio, United States of America
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Amar B. Desai
Roles Conceptualization, Data curation, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing
* E-mail: amar.desai@case.edu
¶‡ WJH and JNPS contributed equally to this work and served as co-first authors. SDM and ABD also contributed equally to this work and served as corresponding author.
Affiliation Department of Medicine, and Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America
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15-PGDH regulates hematopoietic and gastrointestinal fitness during aging
- Won Jin Ho,
- Julianne N. P. Smith,
- Young Soo Park,
- Matthew Hadiono,
- Kelsey Christo,
- Alvin Jogasuria,
- Yongyou Zhang,
- Alyssia V. Broncano,
- Lakshmi Kasturi,
- Dawn M. Dawson
- Published: May 19, 2022
- https://doi.org/10.1371/journal.pone.0268787