Synthesis and biological evaluation of thiazolidine-2-thione derivatives as novel xanthine oxidase inhibitors

• Mu-Xuan Wang ,

  Contributed equally to this work with: Mu-Xuan Wang, Hong-Wei Qin

  Roles Investigation, Methodology, Project administration, Writing – original draft

  Affiliation Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, Jiangsu, P.R. China

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• Hong-Wei Qin ,

  Contributed equally to this work with: Mu-Xuan Wang, Hong-Wei Qin

  Roles Methodology, Validation, Writing – original draft

  Affiliation School of Life Sciences and Bioengineering, Jining University, Qufu, Shandong, P.R. China

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• Chao Liu ,

  Roles Supervision, Validation, Writing – review & editing

  * E-mail: zxliao@seu.edu.cn (ZXL); liuchao555@126.com (CL); moon_s731@hotmail.com (JYS)

  Affiliation Key Laboratory of Novel Food Resources Processing, Ministry of Agriculture and Rural Affairs/Key Laboratory of Agro-Products Processing Technology of Shandong Province/Institute of Agro-Food Science and Technology, Shandong Academy of Agricultural Sciences, Jinan, Shandong, P.R. China

  https://orcid.org/0000-0003-2680-1810

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• Shen-Ming Lv,

  Roles Investigation, Methodology

  Affiliation Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, Jiangsu, P.R. China

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• Jia-Shu Chen,

  Roles Investigation, Methodology

  Affiliation Key Laboratory of Novel Food Resources Processing, Ministry of Agriculture and Rural Affairs/Key Laboratory of Agro-Products Processing Technology of Shandong Province/Institute of Agro-Food Science and Technology, Shandong Academy of Agricultural Sciences, Jinan, Shandong, P.R. China

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• Chun-Gu Wang,

  Roles Investigation, Methodology

  Affiliation Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, Jiangsu, P.R. China

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• Ying-Ying Chen,

  Roles Investigation, Methodology, Validation

  Affiliation Key Laboratory of Novel Food Resources Processing, Ministry of Agriculture and Rural Affairs/Key Laboratory of Agro-Products Processing Technology of Shandong Province/Institute of Agro-Food Science and Technology, Shandong Academy of Agricultural Sciences, Jinan, Shandong, P.R. China

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• Jia-Wei Wang,

  Roles Investigation, Methodology

  Affiliation Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, Jiangsu, P.R. China

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• Jin-Yue Sun ,

  Roles Supervision, Validation, Writing – review & editing

  * E-mail: zxliao@seu.edu.cn (ZXL); liuchao555@126.com (CL); moon_s731@hotmail.com (JYS)

  Affiliation Key Laboratory of Novel Food Resources Processing, Ministry of Agriculture and Rural Affairs/Key Laboratory of Agro-Products Processing Technology of Shandong Province/Institute of Agro-Food Science and Technology, Shandong Academy of Agricultural Sciences, Jinan, Shandong, P.R. China

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• Zhi-Xin Liao

  Roles Supervision, Validation, Writing – review & editing

  * E-mail: zxliao@seu.edu.cn (ZXL); liuchao555@126.com (CL); moon_s731@hotmail.com (JYS)

  Affiliation Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering and Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing, Jiangsu, P.R. China

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