Targeting mitochondrial DNA polymerase gamma for selective inhibition of MLH1 deficient colon cancer growth

• Berna Somuncu,

  Roles Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey

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• Aysegul Ekmekcioglu,

  Roles Formal analysis, Investigation

  Affiliation Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey

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• Fatma Merve Antmen,

  Roles Investigation

  Affiliation Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey

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• Tugce Ertuzun,

  Roles Investigation

  Affiliation Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey

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• Emre Deniz,

  Roles Investigation

  Current address: Department of Oncology, Georgetown University Medical Center, Washington, DC, United States of America

  Affiliation Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey

  https://orcid.org/0000-0002-9635-983X

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• Nazli Keskin,

  Roles Investigation

  Current address: Department of Molecular Biology and Genetics, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey

  Affiliation Molecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey

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• Joon Park,

  Roles Investigation

  Affiliation Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Ilgu Ece Yazici,

  Roles Investigation

  Affiliation Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey

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• Busra Simsek,

  Roles Investigation

  Affiliation Molecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey

  https://orcid.org/0000-0002-5094-6668

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• Batu Erman,

  Roles Formal analysis, Funding acquisition, Investigation, Writing – review & editing

  Affiliations Molecular Biology, Genetics and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey, Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Bogazici University, Istanbul, Turkey

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• Whitney Yin,

  Roles Formal analysis, Funding acquisition, Investigation, Writing – review & editing

  Affiliation Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Burak Erman,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Writing – review & editing

  Affiliation Department of Chemical and Biological Engineering, Koc University, Istanbul, Turkey

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• Meltem Muftuoglu

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: meltem.muftuoglu@acibadem.edu.tr

  Affiliations Department of Medical Biotechnology, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey, Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey

  https://orcid.org/0000-0001-5372-4780

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