A randomized clinical trial demonstrating cell type specific effects of hyperlipidemia and hyperinsulinemia on pituitary function

Rosemary McDonald; Katherine Kuhn; Thy B. Nguyen; Andrew Tannous; Irene Schauer; Nanette Santoro; Andrew P. Bradford

doi:10.1371/journal.pone.0268323

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Open Access

Peer-reviewed

Research Article

A randomized clinical trial demonstrating cell type specific effects of hyperlipidemia and hyperinsulinemia on pituitary function

Rosemary McDonald,

Roles Formal analysis, Investigation, Writing – original draft

Affiliation Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, CO, United States of America
⨯
Katherine Kuhn,

Roles Data curation, Investigation, Project administration, Writing – review & editing

Affiliation Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, CO, United States of America

https://orcid.org/0000-0001-9096-7490

⨯
Thy B. Nguyen,

Roles Investigation

Affiliation Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, CO, United States of America
⨯
Andrew Tannous,

Roles Investigation

Affiliation Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, CO, United States of America
⨯
Irene Schauer,

Roles Investigation, Resources, Writing – review & editing

Affiliations Department of Medicine, Division of Endocrinology, Metabolism & Diabetes, University of Colorado School of Medicine, Aurora, CO, United States of America, Endocrinology Section, Rocky Mountain Regional Veterans Affairs Medical Center, Aurora, CO, United States of America
⨯
Nanette Santoro ,

Roles Conceptualization, Funding acquisition, Writing – review & editing

¶‡ NS and APB are joint senior authors on this work.

Affiliation Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, CO, United States of America
⨯
Andrew P. Bradford

Roles Conceptualization, Investigation, Supervision, Writing – original draft, Writing – review & editing

* E-mail: Andy.Bradford@cuanschutz.edu

¶‡ NS and APB are joint senior authors on this work.

Affiliation Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, CO, United States of America

https://orcid.org/0000-0002-8728-571X

⨯

A randomized clinical trial demonstrating cell type specific effects of hyperlipidemia and hyperinsulinemia on pituitary function

Rosemary McDonald,
Katherine Kuhn,
Thy B. Nguyen,
Andrew Tannous,
Irene Schauer,
Nanette Santoro,
Andrew P. Bradford

Published: May 11, 2022
https://doi.org/10.1371/journal.pone.0268323

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Lipids
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Insulin
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Thyroid-stimulating hormone
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Pituitary gland
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Adiponectin
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Obesity
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Thyroid hormones
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