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Open Access
Peer-reviewed
Research Article
Predictive models in SMA II natural history trajectories using machine learning: A proof of concept study
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Giorgia Coratti ,
Contributed equally to this work with: Giorgia Coratti, Jacopo Lenkowicz
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing
Affiliations Pediatric Neurology, Università Cattolica del Sacro Cuore, Rome, Italy, Centro Clinico Nemo, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy
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Jacopo Lenkowicz ,
Contributed equally to this work with: Giorgia Coratti, Jacopo Lenkowicz
Roles Data curation, Formal analysis, Methodology, Resources, Software, Validation, Writing – original draft, Writing – review & editing
Affiliation Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
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Stefano Patarnello,
Roles Conceptualization, Funding acquisition, Validation, Writing – original draft, Writing – review & editing
Affiliation Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
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Consolato Gullì,
Roles Data curation, Methodology, Validation, Visualization
Affiliation Department of Radiological and Hematological Sciences Fondazione, Policlinico Universitario A. Gemelli, IRCCS Università Cattolica del Sacro Cuore, Largo A. Gemelli, Rome, Italy
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Maria Carmela Pera,
Roles Investigation, Methodology, Visualization
Affiliations Pediatric Neurology, Università Cattolica del Sacro Cuore, Rome, Italy, Centro Clinico Nemo, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy
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Carlotta Masciocchi,
Roles Data curation, Methodology, Visualization
Affiliation Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
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Riccardo Rinaldi,
Roles Data curation, Methodology, Visualization
Affiliation Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
⨯ - Valeria Lovato,
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Antonio Leone,
Roles Data curation, Methodology, Supervision, Visualization
Affiliation Department of Radiological and Hematological Sciences Fondazione, Policlinico Universitario A. Gemelli, IRCCS Università Cattolica del Sacro Cuore, Largo A. Gemelli, Rome, Italy
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Alfredo Cesario,
Roles Funding acquisition, Project administration, Resources, Validation, Visualization
Affiliation Open Innovation Manager, Scientific Directorate, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy
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Eugenio Mercuri
Roles Conceptualization, Data curation, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing
* E-mail: eugeniomaria.mercuri@unicatt.it
Affiliations Pediatric Neurology, Università Cattolica del Sacro Cuore, Rome, Italy, Centro Clinico Nemo, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy
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Predictive models in SMA II natural history trajectories using machine learning: A proof of concept study
- Giorgia Coratti,
- Jacopo Lenkowicz,
- Stefano Patarnello,
- Consolato Gullì,
- Maria Carmela Pera,
- Carlotta Masciocchi,
- Riccardo Rinaldi,
- Valeria Lovato,
- Antonio Leone,
- Alfredo Cesario
- Published: May 5, 2022
- https://doi.org/10.1371/journal.pone.0267930