Design and synthesis of Nrf2-derived hydrocarbon stapled peptides for the disruption of protein-DNA-interactions

• Bianca Wiedemann ,

  Contributed equally to this work with: Bianca Wiedemann, Dominic Kamps, Laura Depta

  Roles Data curation, Formal analysis, Investigation, Validation, Visualization, Writing – original draft

  Affiliation Faculty of Chemistry and Chemical Biology, TU Dortmund University and Drug Discovery Hub Dortmund (DDHD), Zentrum für Integrierte Wirkstoffforschung (ZIW), Dortmund, Germany

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• Dominic Kamps ,

  Contributed equally to this work with: Bianca Wiedemann, Dominic Kamps, Laura Depta

  Roles Formal analysis, Investigation, Validation, Visualization, Writing – review & editing

  Affiliations Faculty of Chemistry and Chemical Biology, TU Dortmund University and Drug Discovery Hub Dortmund (DDHD), Zentrum für Integrierte Wirkstoffforschung (ZIW), Dortmund, Germany, Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany

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• Laura Depta ,

  Contributed equally to this work with: Bianca Wiedemann, Dominic Kamps, Laura Depta

  Roles Formal analysis, Investigation, Validation, Visualization, Writing – review & editing

  Affiliation Faculty of Chemistry and Chemical Biology, TU Dortmund University and Drug Discovery Hub Dortmund (DDHD), Zentrum für Integrierte Wirkstoffforschung (ZIW), Dortmund, Germany

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• Jörn Weisner,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Faculty of Chemistry and Chemical Biology, TU Dortmund University and Drug Discovery Hub Dortmund (DDHD), Zentrum für Integrierte Wirkstoffforschung (ZIW), Dortmund, Germany

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• Jana Cvetreznik,

  Roles Formal analysis

  Affiliation Faculty of Chemistry and Chemical Biology, TU Dortmund University and Drug Discovery Hub Dortmund (DDHD), Zentrum für Integrierte Wirkstoffforschung (ZIW), Dortmund, Germany

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• Stefano Tomassi,

  Roles Formal analysis, Investigation

  Affiliation Department of Pharmacy, University of Naples “Federico II”, Napoli, Italy

  https://orcid.org/0000-0003-3152-4467

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• Sascha Gentz,

  Roles Formal analysis

  Affiliation Protein Chemistry Facility, Max Planck Institute of Molecular Physiology, Dortmund, Germany

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• Jan-Erik Hoffmann,

  Roles Formal analysis

  Affiliation Protein Chemistry Facility, Max Planck Institute of Molecular Physiology, Dortmund, Germany

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• Matthias P. Müller,

  Roles Formal analysis, Writing – review & editing

  Affiliation Faculty of Chemistry and Chemical Biology, TU Dortmund University and Drug Discovery Hub Dortmund (DDHD), Zentrum für Integrierte Wirkstoffforschung (ZIW), Dortmund, Germany

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• Oliver Koch,

  Roles Formal analysis

  Affiliation Institute of Pharmaceutical and Medicinal Chemistry and German Center of Infection Research, Münster, Germany

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• Leif Dehmelt,

  Roles Investigation, Resources, Writing – review & editing

  Affiliations Faculty of Chemistry and Chemical Biology, TU Dortmund University and Drug Discovery Hub Dortmund (DDHD), Zentrum für Integrierte Wirkstoffforschung (ZIW), Dortmund, Germany, Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany

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• Daniel Rauh

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Writing – review & editing

  * E-mail: daniel.rauh@tu-dortmund.de

  Affiliation Faculty of Chemistry and Chemical Biology, TU Dortmund University and Drug Discovery Hub Dortmund (DDHD), Zentrum für Integrierte Wirkstoffforschung (ZIW), Dortmund, Germany

  https://orcid.org/0000-0002-1970-7642

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