Blood mRNA biomarkers distinguish variable systemic and sputum inflammation at treatment initiation of inhaled antibiotics in cystic fibrosis: A prospective non-randomized trial

• Silvia M. Caceres ,

  Contributed equally to this work with: Silvia M. Caceres, Linda A. Sanders, Noel M. Rysavy, Katie R. Poch, Jerry A. Nick, Milene T. Saavedra

  Roles Investigation, Methodology, Project administration, Writing – original draft

  Affiliation Department of Medicine, National Jewish Health, Denver, Colorado, United States of America

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• Linda A. Sanders ,

  Contributed equally to this work with: Silvia M. Caceres, Linda A. Sanders, Noel M. Rysavy, Katie R. Poch, Jerry A. Nick, Milene T. Saavedra

  Roles Data curation

  Affiliations Department of Medicine, National Jewish Health, Denver, Colorado, United States of America, Department of Medicine, University of Colorado Denver, Aurora, Colorado, United States of America

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• Noel M. Rysavy ,

  Contributed equally to this work with: Silvia M. Caceres, Linda A. Sanders, Noel M. Rysavy, Katie R. Poch, Jerry A. Nick, Milene T. Saavedra

  Roles Data curation, Formal analysis

  Affiliation Department of Medicine, National Jewish Health, Denver, Colorado, United States of America

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• Katie R. Poch ,

  Contributed equally to this work with: Silvia M. Caceres, Linda A. Sanders, Noel M. Rysavy, Katie R. Poch, Jerry A. Nick, Milene T. Saavedra

  Roles Data curation, Project administration

  Affiliation Department of Medicine, National Jewish Health, Denver, Colorado, United States of America

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• Caroline R. Jones ,

  Roles Project administration

  ¶‡ CRJ, KP, TEF, RAM, KCM, JLTC, DPN and MS also contributed equally to this work.

  Affiliation Department of Medicine, National Jewish Health, Denver, Colorado, United States of America

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• Kyle Pickard ,

  Roles Project administration

  ¶‡ CRJ, KP, TEF, RAM, KCM, JLTC, DPN and MS also contributed equally to this work.

  Affiliation Department of Medicine, National Jewish Health, Denver, Colorado, United States of America

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• Tasha E. Fingerlin ,

  Roles Methodology, Writing – review & editing

  ¶‡ CRJ, KP, TEF, RAM, KCM, JLTC, DPN and MS also contributed equally to this work.

  Affiliation Center for Genes, Environment, and Health, National Jewish Health, Denver, Colorado, United States of America

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• Roland A. Marcus ,

  Roles Methodology, Writing – review & editing

  ¶‡ CRJ, KP, TEF, RAM, KCM, JLTC, DPN and MS also contributed equally to this work.

  Affiliation Center for Genes, Environment, and Health, National Jewish Health, Denver, Colorado, United States of America

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• Kenneth C. Malcolm ,

  Roles Writing – review & editing

  ¶‡ CRJ, KP, TEF, RAM, KCM, JLTC, DPN and MS also contributed equally to this work.

  Affiliation Department of Medicine, National Jewish Health, Denver, Colorado, United States of America

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• Jennifer L. Taylor-Cousar ,

  Roles Project administration, Writing – review & editing

  ¶‡ CRJ, KP, TEF, RAM, KCM, JLTC, DPN and MS also contributed equally to this work.

  Affiliations Department of Medicine, National Jewish Health, Denver, Colorado, United States of America, Department of Medicine, University of Colorado Denver, Aurora, Colorado, United States of America, Department of Pediatrics, Children’s Hospital Colorado, Aurora, Colorado, United States of America

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• David P. Nichols ,

  Roles Project administration, Writing – review & editing

  ¶‡ CRJ, KP, TEF, RAM, KCM, JLTC, DPN and MS also contributed equally to this work.

  Affiliation Department of Pediatrics, University of Washington, Seattle, Washington, United States of America

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• Jerry A. Nick ,

  Contributed equally to this work with: Silvia M. Caceres, Linda A. Sanders, Noel M. Rysavy, Katie R. Poch, Jerry A. Nick, Milene T. Saavedra

  Roles Formal analysis, Project administration, Writing – review & editing

  Affiliations Department of Medicine, National Jewish Health, Denver, Colorado, United States of America, Department of Medicine, University of Colorado Denver, Aurora, Colorado, United States of America

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• Matthew Strand ,

  Roles Formal analysis, Methodology, Writing – review & editing

  ¶‡ CRJ, KP, TEF, RAM, KCM, JLTC, DPN and MS also contributed equally to this work.

  Affiliation Division of Biostatistics, National Jewish Health, Denver, Colorado, United States of America

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• Milene T. Saavedra

  Contributed equally to this work with: Silvia M. Caceres, Linda A. Sanders, Noel M. Rysavy, Katie R. Poch, Jerry A. Nick, Milene T. Saavedra

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: saavedram@njhealth.org

  Affiliations Department of Medicine, National Jewish Health, Denver, Colorado, United States of America, Department of Medicine, University of Colorado Denver, Aurora, Colorado, United States of America

  https://orcid.org/0000-0001-5962-2064

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