Reduced affinity of calcium sensing-receptor heterodimers and reduced mutant homodimer trafficking combine to impair function in a model of familial hypocalciuric hypercalcemia type 1

• Xiaohua Wang,

  Roles Formal analysis, Investigation, Methodology, Project administration, Writing – original draft

  Current address: Department of Pathology, Orlando Regional Medical Center, Orlando, Florida, United States of America

  Affiliation Division of Pulmonary and Critical Care Medicine, Oregon Health and Science University, Portland, Oregon, United States of America

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• James Lundblad,

  Roles Methodology, Supervision, Writing – review & editing

  Affiliations Division of Endocrinology and Diabetes, Oregon Health and Science University, Portland, Oregon, United States of America, Section of Endocrinology and Diabetes, VA Portland Health Care System, Portland, Oregon, United States of America

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• Stephen M. Smith

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

  * E-mail: smisteph@ohsu.edu

  Affiliations Division of Pulmonary and Critical Care Medicine, Oregon Health and Science University, Portland, Oregon, United States of America, Sections of Pulmonary and Critical Care Medicine and Research & Development, VA Portland Health Care System, Portland, Oregon, United States of America

  https://orcid.org/0000-0002-0331-7615

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