Direct comparison of circulating tumor DNA sequencing assays with targeted large gene panels

Lizhi Yu; Gonzalo Lopez; John Rassa; Yixin Wang; Tara Basavanhally; Andrew Browne; Chang-Pin Huang; Lauren Dorsey; Jin Jen; Sarah Hersey

doi:10.1371/journal.pone.0266889

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Open Access

Peer-reviewed

Research Article

Direct comparison of circulating tumor DNA sequencing assays with targeted large gene panels

Lizhi Yu ,

Contributed equally to this work with: Lizhi Yu, Gonzalo Lopez

Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: David.yu1@bms.com

Affiliation Translational Sciences and Diagnostics, Translation Medicine, Bristol Myers Squibb, Summit, New Jersey, United States of America

https://orcid.org/0000-0002-9513-2916

⨯
Gonzalo Lopez ,

Contributed equally to this work with: Lizhi Yu, Gonzalo Lopez

Roles Data curation, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

Affiliation Translational Bioinformatics, Informatics and Predictive Sciences, Bristol Myers Squibb, Summit, New Jersey, United States of America
⨯
John Rassa,

Roles Conceptualization, Methodology, Project administration, Supervision, Writing – review & editing

Affiliation Translational Sciences and Diagnostics, Translation Medicine, Bristol Myers Squibb, Summit, New Jersey, United States of America
⨯
Yixin Wang,

Roles Conceptualization, Methodology, Resources, Supervision, Writing – review & editing

Affiliation Translational Sciences and Diagnostics, Translation Medicine, Bristol Myers Squibb, Summit, New Jersey, United States of America
⨯
Tara Basavanhally,

Roles Data curation, Formal analysis

Affiliation Translational Bioinformatics, Informatics and Predictive Sciences, Bristol Myers Squibb, Summit, New Jersey, United States of America
⨯
Andrew Browne,

Roles Data curation, Formal analysis

Affiliation Translational Bioinformatics, Informatics and Predictive Sciences, Bristol Myers Squibb, Summit, New Jersey, United States of America
⨯
Chang-Pin Huang,

Roles Conceptualization, Data curation, Methodology, Writing – review & editing

Affiliation Translational Research, Immuno-Oncology and Cell Therapy, Bristol Myers Squibb, Seattle, Washington, United States of America
⨯
Lauren Dorsey,

Roles Investigation

Affiliation Translational Bioinformatics, Informatics and Predictive Sciences, Bristol Myers Squibb, Summit, New Jersey, United States of America
⨯
Jin Jen,

Roles Data curation, Methodology, Resources, Supervision, Writing – review & editing

Affiliation Translational Bioinformatics, Informatics and Predictive Sciences, Bristol Myers Squibb, Summit, New Jersey, United States of America
⨯
Sarah Hersey

Roles Resources, Supervision, Writing – review & editing

Affiliation Translational Sciences and Diagnostics, Translation Medicine, Bristol Myers Squibb, Summit, New Jersey, United States of America
⨯

Direct comparison of circulating tumor DNA sequencing assays with targeted large gene panels

Lizhi Yu,
Gonzalo Lopez,
John Rassa,
Yixin Wang,
Tara Basavanhally,
Andrew Browne,
Chang-Pin Huang,
Lauren Dorsey,
Jin Jen,
Sarah Hersey

Published: April 28, 2022
https://doi.org/10.1371/journal.pone.0266889

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01 Jun 2022
20:54 GMT
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Authors' Statement Posted by dyu633 on 01 Jun 2022 at 20:54 GMT

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Mutation detection
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Mutation
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Cancers and neoplasms
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Insertion mutation
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Circulating tumor DNA
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