Covariate adjustment of spirometric and smoking phenotypes: The potential of neural network models

• Kirsten Voorhies,

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Population Medicine, PRecisiOn Medicine Translational Research (PROMoTeR) Center, Harvard Pilgrim Health Care and Harvard Medical School, Boston, MA, United States of America

  https://orcid.org/0000-0002-0249-4337

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• Ruofan Bie,

  Roles Conceptualization, Formal analysis, Writing – review & editing

  Affiliation Department of Biostatistics, T.H. Chan School of Public Health, Harvard University, Boston, MA, United States of America

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• John E. Hokanson,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Epidemiology, University of Colorado Anschutz, Aurora, CO, United States of America

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• Scott T. Weiss,

  Roles Conceptualization, Writing – review & editing

  Affiliation Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, United States of America

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• Ann Chen Wu,

  Roles Conceptualization, Writing – review & editing

  Affiliations Department of Population Medicine, PRecisiOn Medicine Translational Research (PROMoTeR) Center, Harvard Pilgrim Health Care and Harvard Medical School, Boston, MA, United States of America, Division of General Pediatrics, Department of Pediatrics, Children’s Hospital, Boston, MA, United States of America

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• Julian Hecker,

  Roles Conceptualization, Writing – review & editing

  Affiliation Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, United States of America

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• Georg Hahn,

  Roles Methodology, Validation, Writing – review & editing

  Affiliation Department of Biostatistics, T.H. Chan School of Public Health, Harvard University, Boston, MA, United States of America

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• Dawn L. Demeo,

  Roles Conceptualization, Writing – review & editing

  Affiliation Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, United States of America

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• Edwin Silverman,

  Roles Conceptualization, Writing – review & editing

  Affiliation Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, United States of America

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• Michael H. Cho,

  Roles Conceptualization, Writing – review & editing

  Affiliation Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, United States of America

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• Christoph Lange,

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Biostatistics, T.H. Chan School of Public Health, Harvard University, Boston, MA, United States of America

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• Sharon M. Lutz

  Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

  * E-mail: smlutz@hsph.harvard.edu

  Affiliations Department of Population Medicine, PRecisiOn Medicine Translational Research (PROMoTeR) Center, Harvard Pilgrim Health Care and Harvard Medical School, Boston, MA, United States of America, Department of Biostatistics, T.H. Chan School of Public Health, Harvard University, Boston, MA, United States of America

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