RAD51 is a druggable target that sustains replication fork progression upon DNA replication stress

Sonia Feu; Fernando Unzueta; Amaia Ercilla; Alejandro Pérez-Venteo; Montserrat Jaumot; Neus Agell

doi:10.1371/journal.pone.0266645

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Open Access

Peer-reviewed

Research Article

RAD51 is a druggable target that sustains replication fork progression upon DNA replication stress

Sonia Feu ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

¶‡ SF and FU share first authorship on this work.

Affiliations Dept. Biomedicina, Universitat de Barcelona, Barcelona, Spain, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
⨯
Fernando Unzueta ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

¶‡ SF and FU share first authorship on this work.

Affiliations Dept. Biomedicina, Universitat de Barcelona, Barcelona, Spain, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
⨯
Amaia Ercilla,

Roles Formal analysis, Validation, Writing – review & editing

Affiliation CIC bioGUNE, Basque Research and Technology Alliance (BRTA), Derio, Spain

https://orcid.org/0000-0001-8999-7131

⨯
Alejandro Pérez-Venteo,

Roles Investigation

Affiliation Dept. Biomedicina, Universitat de Barcelona, Barcelona, Spain
⨯
Montserrat Jaumot,

Roles Formal analysis, Writing – review & editing

Affiliations Dept. Biomedicina, Universitat de Barcelona, Barcelona, Spain, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
⨯
Neus Agell

Roles Conceptualization, Data curation, Funding acquisition, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: neusagell@gmail.com

Affiliations Dept. Biomedicina, Universitat de Barcelona, Barcelona, Spain, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

https://orcid.org/0000-0002-1205-6074

⨯

RAD51 is a druggable target that sustains replication fork progression upon DNA replication stress

Sonia Feu,
Fernando Unzueta,
Amaia Ercilla,
Alejandro Pérez-Venteo,
Montserrat Jaumot,
Neus Agell

Published: August 15, 2022
https://doi.org/10.1371/journal.pone.0266645

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