The Tsallis generalized entropy enhances the interpretation of transcriptomics datasets

Nicolas Dérian; Hang-Phuong Pham; Djamel Nehar-Belaid; Nicolas Tchitchek; David Klatzmann; Vicaut Eric; Adrien Six

doi:10.1371/journal.pone.0266618

Loading metrics

Open Access

Peer-reviewed

Research Article

The Tsallis generalized entropy enhances the interpretation of transcriptomics datasets

Nicolas Dérian,

Roles Conceptualization, Investigation, Methodology

Affiliations Sorbonne Université, INSERM, UMR-S 959, Immunology-Immunopathology- Immunotherapy (i3), Paris, France, AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (i2B), Paris, France
⨯
Hang-Phuong Pham,

Roles Investigation, Methodology

Affiliation IL-TOO Pharma, Paris, France
⨯
Djamel Nehar-Belaid,

Roles Conceptualization, Investigation, Methodology

Affiliations Sorbonne Université, INSERM, UMR-S 959, Immunology-Immunopathology- Immunotherapy (i3), Paris, France, AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (i2B), Paris, France, The Jackson Laboratory for Genomic Medicine, Farmington, CT, United States of America
⨯
Nicolas Tchitchek,

Roles Conceptualization, Investigation, Methodology

Affiliations Sorbonne Université, INSERM, UMR-S 959, Immunology-Immunopathology- Immunotherapy (i3), Paris, France, AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (i2B), Paris, France
⨯
David Klatzmann,

Roles Investigation, Methodology

Affiliations Sorbonne Université, INSERM, UMR-S 959, Immunology-Immunopathology- Immunotherapy (i3), Paris, France, AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (i2B), Paris, France
⨯
Vicaut Eric,

Roles Investigation, Methodology

Affiliation APHP, Hôpitaux Saint-Louis Lariboisière, Univ Paris 07, Unité de recherche clinique, UMR 942, Paris, France
⨯
Adrien Six

Roles Investigation, Methodology, Supervision

* E-mail: adrien.six@sorbonne-universite.fr

Affiliations Sorbonne Université, INSERM, UMR-S 959, Immunology-Immunopathology- Immunotherapy (i3), Paris, France, AP-HP, Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (i2B), Paris, France
⨯

The Tsallis generalized entropy enhances the interpretation of transcriptomics datasets

Nicolas Dérian,
Hang-Phuong Pham,
Djamel Nehar-Belaid,
Nicolas Tchitchek,
David Klatzmann,
Vicaut Eric,
Adrien Six

Published: April 21, 2022
https://doi.org/10.1371/journal.pone.0266618

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Transcriptome analysis
Is the Subject Area "Transcriptome analysis" applicable to this article?

Thanks for your feedback.
Entropy
Is the Subject Area "Entropy" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Shannon index
Is the Subject Area "Shannon index" applicable to this article?

Thanks for your feedback.
Simpson index
Is the Subject Area "Simpson index" applicable to this article?

Thanks for your feedback.
Pregnancy
Is the Subject Area "Pregnancy" applicable to this article?

Thanks for your feedback.
Principal component analysis
Is the Subject Area "Principal component analysis" applicable to this article?

Thanks for your feedback.
Uterus
Is the Subject Area "Uterus" applicable to this article?

Thanks for your feedback.